000			03010cam a2200337 a 4500
003			EG-GiCUC
005			20250223031953.0
008			180404s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.19.M.Sc.2017.Ma.D
100	0		_aMarwa Mohammed Mohammed Ghobashy
245	1	0	_aDetection of carbapenemase - producing enterobacteriaceae by the rapidec CARBA NP test / _cMarwa Mohammed Mohammed Ghobashy ; Supervised Amal Shafik Balbaa , Basma Ahmed Elawady
246	1	5	_aالكشف عن البكتريا المعويه المنتجه لانزيم الكاربابيناميز عن طريق استخدام اختبار الرابيدك كاربا ان بي
260			_aCairo : _bMarwa Mohammed Mohammed Ghobashy , _c2017
300			_a104 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology
520			_aIntroduction: Rapid dissemination of carbapenem resistant Enterobacteriaceae represents a major threat to patient care and public health. Rapid detection and identification provides effective treatment and proper infection control measures. Aim of the work: The purpose of the study was to detect carbapenemase-producing Enterobacteriaceae with the Rapidec carba np test. Materials and methods: The study was conducted on 101 clinical samples. Sixty Enterobacteriaceae isolates were identified to species level by the API 20E then screened for carbapenemase-production by ertapenem disk diffusion method and Minimum inhibitory concentration methods. Confirmation was done by the Modified Hodge Test and the Rapidec carba np test. Results: Among the 60 Enterobacteriaceae isolates, E.coli was the most commonly encountered (51.6%), followed by K. pneumoniae (38.3%), K. oxytoca (3.3%), E. cloacae (1.6%) and P. mirabilis (5%). Out of the 60 isolates, 25 isolates (41.6%) were screened to be carbapenem resistant by ertapenem disk diffusion (ETP) and 35 isolates (58.3%) were sensitive. Twenty seven isolates (45%) were screened positive by MIC and 33 isolates (55%) were negative. Twenty five isolates (41.6%) were confirmed to be carbapenem resistant by the Modified Hodge test (MHT) and 35 isolates (58.3%) were sensitive. Twenty seven isolates (45%) were confirmed to be carbapenem resistant by the Rapidec carba np test and 33 isolates (55%) were sensitive. Conclusions: The Rapidec carba np test overall sensitivity was 100% and specificity was 94.29% in detecting carbapenemase producing Enterobacteriaceae isolates
530			_aIssued also as CD
653		4	_aEnterobacteriaceae
653		4	_aModified Hodge Test
653		4	_aRapidec CARBA NP test
700	0		_aAmal Shafik Balbaa , _eSupervisor
700	0		_aBasma Ahmed Elawady , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c65756 _d65756