000			03060cam a2200325 a 4500
003			EG-GiCUC
008			180509s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2017.Ma.B
100	0		_aMahmoud Ahmed Sayed Ismail
245	1	0	_aBone density in pediatric patients on regular hemodialysis and post renal transplantation / _cMahmoud Ahmed Sayed Ismail ; Supervised Samuel Helmi Makar , Safaa Mohamed Abdelrahman , Engy Adel Ali
246	1	5	_aقياس كثافة العظام فى الاطفال المنتظمين على غسيل الكلى الدموى والاطفال الذين تم عمل زرع كلى لهم
260			_aCairo : _bMahmoud Ahmed Sayed Ismail , _c2017
300			_a167 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aBackground: Successful kidney transplantation and proper regular hemodialysis corrects many of the metabolic abnormalities associated with development of renal osteodystrophy, but despite a wellfunctioning graft and efficient dialysis, osteopenia and osteoprosis, remains prevalent in adult and pediatric kidney recipients and patients on regular hemodialysis, The factors that affect the bone mineral density (BMD) and the long term course of BMD after transplantation and regular hemodialysis in children is still not been adequately studied. Methods& Results: We performed a cross sectional study to determine BMD in 60 patients Group } will be 30 children with ESRD on regular hemodialysis HD; Group S will be 30 children with post renal transplant TX in in Nephrology Unit, Cairo University Children{u2019}s Hospital by dual energy x-ray absorptiometry at various time intervals after transplantation and hemodialysis (mean duration after transplantation was 4.047 ± 1.92 years, and 4.81±3.49 years in hemoldilysis ). The mean ± SD for BMD was -2.127± 1.64 and -2.48± 2.09 for lumbar 2-4 spine in renal TX & HD group respectively corrected for body surface area. Osteopenia/osteoporosis were present in about two thirds of patients. The signi{uFB01}cant risk factors for osteopenia/osteoporosis using univariate analysis was the cumulative dose of steroids/m2 surface area, graft dysfunction in TX group &may be the duration in HD group.Conclusion: osteopenia and osteoporosis are common in pediatric renal transplant patients. The cumulative steroid dose was the major predictor for bone loss &increase risk of fracture even without evident clinical manifestation to fractures
530			_aIssued also as CD
653		4	_aBone mineral density
653		4	_aPediatric renal transplantation
653		4	_aPost-transplant bone disease
700	0		_aEngy Adel Ali , _eSupervisor
700	0		_aSafaa Mohamed Abdelrahman , _eSupervisor
700	0		_aSamuel Helmi Makar , _eSupervisor
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c66159 _d66159