000			03572cam a2200325 a 4500
003			EG-GiCUC
008			180519s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.23.M.Sc.2017.Ro.P
100	0		_aRoa Abdulrahim Hassan Eltagy
245	1	0	_aProspective study comparing heart dose using conventional free breathing technique and Voluntary Deep Inspiration Breath Holding (vDIBH) technique in post-operative radiotherapy for patients with left breast cancer / _cRoa Abdulrahim Hassan Eltagy ; Supervised Hanaa Attiya , Samy Elbadawy , Mohammed Mahmoud
246	1	5	_aدراسة استطلاعية لمقارنة جرعة القلب باستخدام تقنية التنفس الحر التقليدية وتقنية التنفس العميق القابضة في المرضى الذين يتلقون العلاج الاشعاعي بالثدي الايسر
260			_aCairo : _bRoa Abdulrahim Hassan Eltagy , _c2017
300			_a113 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Oncology (Clinical )
520			_aAim:This is a prospective dosimetric study including patients with left sided breast cancer to compare doses delivered to critical organs at risk (mean heart dose, V10-heart, V20-heart, V25-heart, Left Anterior Descending (LAD) artery, and lungs between conventional free-breathing simulation technique and deep-inspiration breath holding (DIBH) technique, to assess feasibility of DIBH technique in lowering radiation exposure to the heart and lungs without compromising coverage of left breast or chest wall, and to evaluate effect of cardiac rotation on LAD artery dose. Patients and methods:Sixty-six women with left breast cancer needing post-operative radiotherapy were accrued from Radiotherapy department, National Cancer Institute, Cairo from November 2015 to December 2016. All patients were coached on proper method of breath holding and underwent CT simulation during free breathing and DIBH techniques. All patients were planned by 3D conformal technique. Results:Using DIBH technique, all patients, with the exception of one, had lower heart, LAD artery, and left lung doses with statistically significant difference whether they underwent CBS or MRM compared with free breathing technique. Patients who had a unilateral disease, had highly significant lower heart, LAD artery, and left lung doses (p-value <0.001) using DIBH, however, patients who received bilateral breast/chest wall irradiation didn{u2019}t have statistically significant lower doses.Patients who received left axillary/SCV irradiationhad highly significant lower ipsilateral (left) lung doses using DIBH technique than free breathing technique. Patients who received IM nodal irradiation, with wide tangential fields, showed statistically significant lower doses regarding heart and LAD artery between both techniques. In our study, cardiac rotation played a significant role only during DIBH technique, where patients with clockwise rotation had the lowest LAD artery doses and patients with counterclockwise rotation had the highest doses
530			_aIssued also as CD
653		4	_aBreast cancer
653		4	_aBreath holding
653		4	_aRadiotherapy
700	0		_aHanaa Attiya , _eSupervisor
700	0		_aMohammed Mahmoud , _eSupervisor
700	0		_aSamy Elbadawy , _eSupervisor
905			_aShimaa _eCataloger
905			_eRevisor
942			_2ddc _cTH
999			_c66235 _d66235