000			03299cam a2200325 a 4500
003			EG-GiCUC
008			180531s2017 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2017.Ma.P
100	0		_aManar Ahmed Ahmed Elkazzaz
245	1	0	_aPulmonary arterial hypertension and pulmonary vascular disease in children with congenital left to right shunt / _cManar Ahmed Ahmed Elkazzaz ; Supervised Faten Mohammad Abdalaziz , Amira Esmat Altantawy , Aya Mohammad Fattouh
246	1	5	_aأرتفاع ضغط الشريان الرئوي و أمراض الأوعية الدموية الرئوية في الأطفال المصابين بالعيوب الخلقية في القلب المسببة لسريان الدم من الجهة اليسرى إلى الجهة اليمنى
260			_aCairo : _bManar Ahmed Ahmed Elkazzaz , _c2017
300			_a168 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aThis study was conducted to determine the factors which reflect the degree of pulmonary hypertensive state related to congenital left to right shunt lesions and the expected operability criteria.Subject and method:A retrospective study was conducted to revise the electronically stored files of all children with left to right shunt presented to the catheterization laboratory for haemodynamic study in Cairo University Children Hospital between January 2010 and September 2015. The study included 85 patients with congenital left to right shunt atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA) and endocardial cushion defect (ECD). They were all referred to catheterization laboratory to undergo diagnostic cardiac catheterization. The following data were collected; demographic data, CXR, ECG, Echocardiography details and Cardiac catheterization findings including angiographic confirmation of lesions and haemodynamic data.Results:The patients{u2019} ages ranged between 5 months and 18 years. Their Final operability is 70.6%, while final inoperability is 24.7% and 4.7% have no enough data. Being operable on final criteria is significantly related to mPAP (Room air (R.A.), cut off value = 54; Hyperoxia (H.O.), cut off value =49.5), Qp/Qs (R.A., cut off value = 1.21; H.O., cut off value = 3.70), Pp/Ps (H.O., cut off value = 0.69), Rp/Rs (R.A., cut off value = 0.50; H.O., cut off value = 0.15), PVR/SVR (R.A., cut off value = 0.73; H.O., cut off value = 0.17), PVRI (R.A., cut off value = 6; H.O., cut off value = 1.5), Pulmonary artery saturation (H.O., cut off value = 94.5), PACI (R.A., cut off value = 0.52), Age (3.1 years has a high sensitivity to operability, 1.2 years has a high specificity to inoperability)
530			_aIssued also as CD
653		4	_aCardiac catheterization haemodynamics
653		4	_aLeft to right shunt cardiac lesions
653		4	_aPulmonary hypertension
700	0		_aAmira Esmat Altantawy , _eSupervisor
700	0		_aAya Mohammad Fattouh , _eSupervisor
700	0		_aFaten Mohammad Abdalaziz , _eSupervisor
905			_aEnas _eCataloger
905			_aNazla _eRevisor
942			_2ddc _cTH
999			_c66416 _d66416