000 03075cam a2200349 a 4500
003 EG-GiCUC
005 20250223032020.0
008 180709s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2017.Ze.C
100 0 _aZenab Abdelsamie Abdelwadood Abdelraheman
245 1 0 _aClinico-etiological profile of neonatal seizures /
_cZenab Abdelsamie Abdelwadood Abdelraheman ; Supervised Lobna Abdelgawad Mansour , Reem Nabil Said , Marian Yuosry Fahmy
246 1 5 _aصوره اكلينيكيه مسببه لتشنجات حديئى الولادة
260 _aCairo :
_bZenab Abdelsamie Abdelwadood Abdelraheman ,
_c2017
300 _a190 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Incidence of seizures is highest during the neonatal period, and it is considered a medical emergency that necessitate proper clinical and etiological assessment. Objective: To figure out the different etiologies and incidence of neonatal seizures among newborns admitted at NICU Cairo University hospital, thus helping for appropriate diagnosis and proper management. Methodology: The present study included 60 neonates presenting with seizures admitted at NICU Cairo University hospital during the period of one year from May 2014 to May 2015. Baseline data was collected including antenatal history, perinatal history and evidence of HIE (hypoxic ischemic encephalopathy), description of seizures and complete examination. For all cases, serum glucose, calcium, sodium, magnesium, complete blood counts, serum creatinine, liver function tests, ABGs, cranial ultrasound and EEG were done. Second line investigations (blood culture, screening for inborn error of metabolism) were done in selected neonates. Modes of management were also recorded. Descriptive statistics were applied for analysis. Results: Among total 60 cases of neonatal seizures, 24 (40%) cases had Hypoxic ischemic encephalopathy, followed by septicemia in 10(16.7%) cases, Interventricular hemorrhage& Hypocalcaemia were detected in equal ratio 8(13.3%)cases, Intracranial hemorrhage in 4(6.7%) cases, Kernicterus and metabolic were found in 3(5%)&2(3.3%) cases respectively. Majority of cases presented with myoclonic (36.7%) and mixed (28.3%) type of seizures Conclusion: The commonest cause of seizures in this study was perinatal asphyxia with majority presenting in the first 72hrs. Myoclonic seizures were the commonest type of seizure observed
530 _aIssued also as CD
653 4 _aClinical
653 4 _aEtiology
653 4 _aNeonatal seizures
700 0 _aLobna Abdelgawad Mansour ,
_eSupervisor
700 0 _aMarian Yuosry Fahmy ,
_eSupervisor
700 0 _aReem Nabil Said ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c66705
_d66705