000 01514cam a2200277 a 4500
003 EG-GiCUC
005 20250223032021.0
008 180711s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2017.Es.E
100 0 _aEsraa Osama Abdelaziz Mostafa
245 1 0 _aEffect of thymoquinone on Ü7 nicotinic acetylcholine receptor in LPS- induced neuroinflammatory Alzheimer's disease rat model /
_cEsrss Osama Abdelaziz Mostafa ; Supervised Ola Heikal , Lobna Abdelaal Kassem
260 _aCairo :
_bEsrss Osama Abdelaziz Mostafa ,
_c2017
300 _a139 Leaves :
_bcharts , facsimiles ;
_c30cm
502 _aThesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and toxicology
520 _aAlzheimer's disease (AD) is a neurodegenerative disorder resulting from the loss of cholinergic nerurons in the brain. It has been reported that Ü7 nicotinic acetylcholine receptors(Ü7 nAChRs) play an important role in cognitive processes representing a durg target for treating congnitive deficits. Ü7 nAChRs agonists cause memory enhancement through phosphorylation of cAMP response element binding protein (CREB)
700 0 _aLobna Abdelaal Kassem ,
_eSupervisor
700 0 _aOla Heikal ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c66737
_d66737