000			02248cam a2200349 a 4500
003			EG-GiCUC
005			20250223032021.0
008			180809s2017 ua f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.08.03.M.Sc.2017.Fa.A
100	0		_aFatma Ahmed Shalaby
245	1	0	_aAnalytical study of some pharmaceutical nitrogenated cyclic compounds / _cFatma Ahmed Shalaby ; Supervised Laila Elsayed Abdelfatah , Lories Ibrahim Bebawy , Ali Mohamed Yehia
246	1	5	_aدراسة تحليلية لبعض المركبات الصيدلية الحلقية المحتوية علي نيتروجين
260			_aCairo : _bFatma Ahmed Shalaby , _c2017
300			_a125 P. ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520			_aThis work is concerned with stability indicating methods for determination of some drugs containing cyclic nitrogen including; zafirlukast (ZAF), aprepitant (APR). In this thesis different analytical techniques were adopted, namely, TLC-densitometric, spectrophotometric, spectrofluorimetric, chemometric, liquid chromatography, for the determination of the previously mentioned compounds in their pure powder, laboratory prepared mixtures and dosage forms. In part I; general introduction and literature review of ZAF and APR were described. In part II; different analytical methods were described for the determination of ZAF in presence of its alkaline degradates. Including; TLC-densitometry, second derivative (D2) spectrophotometry, specerofluorimetry, colorimetry. In part III; different analytical methods were described for the determination of APR in presence of its acid degradates. Including; TLC-densitometry, HPLC method, chemometry
530			_aIssued also as CD
653		4	_aAprepitant
653		4	_aTLC-densitometry
653		4	_aZafirlukast
700	0		_aAli Mohamed Yehia , _eSupervisor
700	0		_aLaila Elsayed Abdelfatah , _eSupervisor
700	0		_aLories Ibrahim Bebawy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c66741 _d66741