000 01404cam a2200277 a 4500
003 EG-GiCUC
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008 180715s2017 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aGift
097 _aM.Sc
099 _aCai01.34.M.Sc.2017.Li.N
100 0 _aLiza Samir Samy Botros
245 1 0 _aNovel strychnine dimers as bivalent ligands targeting glycine receptors /
_cLiza Samir Samy Botros ; Supervised Darius P. Zlotos
246 1 5 _aمتشابهات ستركنين ثنائية التركيب جديدة كمثبطات لمستقبلات الجلايسين
260 _aCairo :
_bLiza Samir Samy Botros ,
_c2017
300 _a128 Leaves :
_bcharts ;
_c30cm
502 _aThesis (M.Sc.) - German University - Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
520 _aStrychnine in the major alkaloid from the seeds of Strychnos nux-vomica and strychnos ignati. As a natural product, its structure has been optimized for strong interactions with biological macromolecules through evolutionary selection. Its most pronounced pharmacological action is an antagonistic activity at glycine receptors (GlyRs)
700 0 _aDarius P. Zlotos ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c66770
_d66770