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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2018.Ph.C
100 0 _aPhoebe Nabil Ibrahim Bishara
245 1 0 _aCorrelation between serum IL-23 and pulmonary functions in asthmatic children /
_cPhoebe Nabil Ibrahim Bishara ; Supervised Mona Mostafa Elfalaki , Manal Michel Wilson , Christine William Shaker Basanti
246 1 5 _aالعلاقـة بين انترلوكين-23 بالـدم ووظـائـف الرئـة فى الأطـفال المصـابـين بالـربـو
260 _aCairo :
_bPhoebe Nabil Ibrahim Bishara ,
_c2018
300 _a258 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: The circulating levels of IL-23 and its functional consequence in asthmatic children are still lacking. Therefore, the aims of the present study were to evaluate serum IL-23 levels in children with asthma compared with healthy controls and to correlate them to clinical severity of bronchial asthma and to pulmonary function tests. Methods: Forty five asthmatic children and forty five healthy children were evaluated from March, 2014 to March, 2015. Pulmonary functions were performed in all asthmatic children and blood eosinphils, total serum IgE and serum IL-23 were performed in all asthmatic and healthy children. Results: Total serum IgE, blood eosinophils and serum IL-23 levels were higher in asthmatic than in healthy children. IL-23 had an inverse correlation with PFT with no significant relation with severity of asthma. Conclusions: IL-23 can be used as a suitable biomarker for the inflammation of the airways in asthmatic children
530 _aIssued also as CD
653 4 _aBiomarker
653 4 _aBronchial Asthma
653 4 _aInterleukin-23
700 0 _aChristine William Shaker Basanti ,
_eSupervisor
700 0 _aManal Michel Wilson ,
_eSupervisor
700 0 _aMona Mostafa Elfalaki ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c67196
_d67196