000 02701cam a2200349 a 4500
003 EG-GiCUC
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008 180830s2017 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2017.Ah.P
100 0 _aAhmed Mazher Abdelmotaleb Elkholy
245 1 0 _aPresepsin in early detection of sepsis in pediatric cardiac ICU patient /
_cAhmed Mazher Abdelmotaleb Elkholy ; Supervised Sonia Ali Elsaiedi , Inas Abdelsattar Saad , Sahar Abdelatty Sharaf
246 1 5 _aاستخدام البريسيبسن في الكشف المبكر عن تسمم الدم بين مرضي رعاية القلب المركزة
260 _aCairo :
_bAhmed Mazher Abdelmotaleb Elkholy ,
_c2017
300 _a143 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground In face of catastrophe of sepsis, early antibiotics are the single most efficient intervention. Current diagnostics modalities are hampered by delayed results, poor sensitivity and specificity. So there urgent need for biomarker that is more fast and reliable. Aim of the work Evaluation of role of Presepsin as early marker of sepsis in Pediatric Cardiac Intensive Care Unit (PCICU) patients. Methodology The study included 30 cases and 15 controls selected from infants with congenital heart disease (CHD) admitted to PCICU without sepsis and observed tell sepsis onset. In cases the sample at sepsis onset and the one before it, and in controls any sample were taken and analyzed for presepsin using ELISA technique. Results Presepsin was found to havepoor diagnostic. Furthermore it was revealed that presepsin level doesn{u2019}t correlate with. Conclusion & recommendation Presepsin was found to be non-beneficial as both as diagnostic and prognostic tool in pediatric sepsis, but this needed to be reassessed in larger group of patient. Furthermore, more studies needed to be done in area of presymptomatic sepsis diagnosis as well as evaluating role of presepsin and other biomarkers in different study populations and in different causes of infection
530 _aIssued also as CD
653 4 _aCongenital heart disease (CHD)
653 4 _aPediatric Cardiac Intensive Care Unit (PCICU)
653 4 _aPresepsin
700 0 _aInas Abdelsattar Saad ,
_eSupervisor
700 0 _aSahar Abdelatty Sharaf ,
_eSupervisor
700 0 _aSonia Ali Elsaiedi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c67198
_d67198