| 000 | 02398cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032037.0 | ||
| 008 | 180902s2017 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.09.14.Ph.D.2017.No.M | ||
| 100 | 0 | _aNoha Shaban Aboelyazeed | |
| 245 | 1 | 0 |
_aMolecular and protein levels assessment of oncostatin-m in oral squamous cell carcinoma : _bIn vitro study / _cNoha Shaban Aboelyazeed ; Supervised Louloua Mohamed Fathi , Amal Hassan Abdelrahman , Dina Sabry Abdelfattah |
| 246 | 1 | 5 |
_aالتقييم الجزيئي والبروتيني للانكوستاتين-م للسرطانات الفموية الحرشفية : _bدراسة خارجية |
| 260 |
_aCairo : _bNoha Shaban Aboelyazeed , _c2017 |
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| 300 |
_a102 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University -Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology | ||
| 520 | _aBackground: Growth of oral squamous cell carcinoma is generally associated with an inflammatory component. It is hypothesized that tumor cellsevade the growth inhibitory effects of cytokines present in the tumor microenvironment. Oncostatin-M (OSM) is an inflammatory cytokine produced by macrophages and T lymphocytes as well as tumor cells, it inhibits the proliferation and induces differentiation of a number of types of tumors. This study aimed to study OSM expression on both gene and protein levels. Methods:in vitro study done on thirty (OSCC) cases obtained from paraffin blocks and ten normal epithelial tissues used as control. For each case immunohistochemical examination of OSM protein intissues as well as quantitative real time polymerase chain reaction(RT-PCR) were done for determination of expression of both OSM gene and its specific receptor, finally results were statistically analyzed using ANOVA test | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aInflammatory cytokine | |
| 653 | 4 | _aOncostatin-m | |
| 653 | 4 | _aOral Squamous cell carcinoma | |
| 700 | 0 |
_aAmal Hassan Abdelrahman , _eSupervisor |
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| 700 | 0 |
_aDina Sabry Abdelfattah , _eSupervisor |
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| 700 | 0 |
_aLouloua Mohamed Fathi , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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_c67237 _d67237 |
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