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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.28.Ph.D.2018.Do.E
100 0 _aDouaa Elsaied Elsherbiny
245 1 0 _aEffect of application of sustained lung inflation at birth on improving respiratory outcome of preterm infants with respiratory distress syndrome /
_cDouaa Elsaied Elsherbiny ; Supervised Iman Fathy Iskander , Salma Zoher Alhoshy , Walaa Sharany Aboalhamad
246 1 5 _aتأثير تطبيق النفخ الرئوى المستمر عند الولادة على تحسين نتائج التنفس لدى الأطفال الخدج الذين يعانون من متلازمة ضيق التنفس
260 _aCairo :
_bDouaa Elsaied Elsherbiny ,
_c2018
300 _a136 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Sustained lung inflation (SI) is an alternative method for lung recruitment in preterm infants at birth. There is lack of knowledge about the target population who will best benefit from this maneuver. Methods: A total of 160 infants with gestational age {u2265}27{u2264}32 weeks at birth were randomly assigned to receive either SI using a pressure of 20 cmH2O for 15 seconds followed by nasal CPAP of 5 cm H₂O (intervention group) or nasal CPAP alone, of 5 cm H₂O (control group), through an appropriate mask and a T-piece resuscitator. Mechanical ventilation (MV) within the first 72 hours of life was our primary outcome. Other outcomes included broncho-pulmonary dysplasia and death. Results: Although MV in the first 72 hours was not significantly lower in SI group (44 out of 80, 55%) when compared to control group (52 out of 80, 65%); P=0.145, there was a trend towards that. However among infants with gestational age <30 weeks (n=65), MV in the first 72 hours was significantly lower in SI group (19 out of 35, 54.3%), when compared to control group (26 out of 30, 86.7%); P=0.005. Also, among infants who needed advanced resuscitation; with more than oxygen and tactile stimulation (n=98), MV in the first 72 hours was significantly lower in SI group (34 out of 53, 64%) when compared to control group (40 out of 45, 89%); P=0.005. Conclusion: SI decreases the need for MV in the first 72 hours when applied to infants with gestational age <30 weeks or when given as a rescue approach for infants who need advanced resuscitation with more than oxygen and tactile stimulation
530 _aIssued also as CD
653 4 _aMechanical ventilation
653 4 _aPerterm infants
653 4 _aSustained lung inflstion
700 0 _aIman Fathy Iskander ,
_eSupervisor
700 0 _aSalma Zoher Alhoshy ,
_eSupervisor
700 0 _aWalaa Sharany AboAlhamad ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c67618
_d67618