000 03366cam a2200349 a 4500
003 EG-GiCUC
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008 180923s2017 ua h f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.22.M.Sc.2017.Za.C
100 0 _aZainab Ahmed Mohamed Zaki
245 1 0 _aComparison of early and delayed whole body scans after 131I therapy in detection of thyroid tissue in patients with well differentiated thyroid cancer /
_cZainab Ahmed Mohamed Zaki ; Supervised Shawki Elhaddad , Abdalla Eltawil , Jehan Ahmed Younis
246 1 5 _aمقارنة المسح المبكر و المتأخر على الجسم كله بعد الجرعات العلاجية من اليود المشع فى تشخيص فى مرضى أورام الغدة الدرقية
260 _aCairo :
_bZainab Ahmed Mohamed Zaki ,
_c2017
300 _a85 P. :
_bfacsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Nuclear Medicine
520 _aObjectives: To compare the early and delayed images of whole body post therapy scans in detection of residual thyroid tissues and iodine avid distant metastases. Methods: This ongoing prospective study recruited 30 patients known to have differentiated thyroid carcinoma with history of near total thyroidectomy referred for receiving RAI ablative{u0338}therapeutic doses. Patients underwent dual imaging after receiving 131-I doses; early post therapy whole body imaging was performed on the third to fifth day post treatment and delayed whole body imaging was performed on the seventh to tenth day after treatment. Studies were read independently by two nuclear medicine physicians. Thyroid residues, distant iodine avid lesions, left shoulder (for background correction) and liver counts were taken by drawing a fixed region of interest (ROI) around each in both early and delayed imagesthen calculating ratios between residual tissue to background (RBR), residual tissue to liver (RLR) and distant lesion to background ratio (LBR) and comparing the mean of each ratio in early and delayed imagesand calculating a P value for each. Mean number of overall lesions in early and delayed imaging and mean liver countswere compared as well. Results: The uptake ratios from 27 thyroid remnants in 27 patients and 19 distant lesions in 6 patients were compared. The mean RBR on the early scan (17.1±18) was significantly higher than that on the delayed scan (16.1±18.9; p=0.002).furthermore, the mean RLR on the early scan (7.6±17.7) was significantly higher than that on the delayed scan (6.4±14.9; p=0.001) the mean liver count on the early scan .meanwhile, the mean LBR on the early scan (13.25±7) compared to that on the delayed scan (11.99±7.3; p=scan (13.25±7) compared to that on the delayed scan (11.99±7.3; p=0.4) showed no statistical significant difference
530 _aIssued also as CD
653 4 _aDifferentiated thyroid cancer
653 4 _aEarly imaging
653 4 _aRadioactive iodine
700 0 _aAbdalla Eltawil ,
_eSupervisor
700 0 _aJehan Ahmed Younis ,
_eSupervisor
700 0 _aShawki Elhaddad ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c67630
_d67630