000 02758cam a2200349 a 4500
003 EG-GiCUC
005 20250223032100.0
008 181015s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.02.Ph.D.2018.Mo.B
100 0 _aMona Moaness Abdelmoneam Mohamed
245 1 0 _aBioresorbable electrospun matrices based on doped nano-phosphate glass/polymer composite for drug delivery applications /
_cMona Moaness Abdelmoneam Mohamed ; Supervised Mervat Elsayed Mohamed , Heba Mohamed Kamal , Emad Abdelsalam Elmeliegy
246 1 5 _aتحضير دعامات مغزولة كهربيا قابلة للتحلل الحيوى من متوالفات الزجاج الفوسفاتي النانومترى المطعم والبوليمر لتطبيقات توصيل الدواء
260 _aCairo :
_bMona Moaness Abdelmoneam Mohamed ,
_c2018
300 _a202 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry
520 _aThe main objective of our study is the design, fabrication and characterization of electrospun bioresorbable composites matrices for localized and controlled ciprofloxacin delivery. They were proposed for effective management of bone regeneration and associated infections. Ciprofloxacin loaded bioresorbable nanofiber mats based on, the poly({u03F5}-caprolactone)(PCL)/poly (Nvinyl- 2-pyrrolidone) (PVP)composite and modified by the addition of phosphate glass nanoparticles ,were prepared by electrospinning . Phosphate based glasses nanoparticles incorporated with different La₂O₃ contents (0, 5 and 10 mol. %) were prepared successfully by a modified alkoxide sol gel method. They were coded as P, PL5 and PL10 respectively. The obtained glasses were characterized by different analytical techniques, such as, x-ray diffraction analysis(XRD), Thermogravimetric and differential scanning calorimetric analyses (TGA/DSC), transmission electron microscopy (TEM), Fourier transformer infrared spectrophotometer (FTIR) and energy dispersive xray spectroscopy analysis (EDX). Textural properties, such as specific surface area, total pore volume and average pore size were evaluated by the high-speed gas sorption analyzer
530 _aIssued also as CD
653 4 _aLanthanum
653 4 _aPhosphate glass nanoparticles
653 4 _aSol-gel
700 0 _aEmad Abdelsalam Elmeliegy ,
_eSupervisor
700 0 _aHeba Mohamed Kamal ,
_eSupervisor
700 0 _aMervat Elsayed Mohamed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c67993
_d67993