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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2018.Ne.C
100 0 _aNesma Mamdouh Ahmed Abdalraheem
245 1 0 _aCardiac evaluation for patients with primary hyperoxaloria type I using cardiac mri and non-conventional echocardiography /
_cNesma Mamdouh Ahmed Abdalraheem ; Supervised Soha Mohammed Mohammed Emam , Safaa Mohammed Abdalrahman , Mohammed Talaat Ali
246 1 5 _aتقييم حالة القلب في المرضى الذين يعانون من فرط أوكسالات البول الأولي عن طريق استخدام الرنين المغناطيسي و الموجات الصوتيه الغير تقليديه على القلب
260 _aCairo :
_bNesma Mamdouh Ahmed Abdalraheem ,
_c2018
300 _a127 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground : Primary hyperoxaluria type I (PH I) is an inborn error of metabolism resulting in increased endogenous production of oxalate leading to excessive urinary oxalate excretion, followed with renal damage and consecutive systemic oxalosis, including cardiac affection. Aim of the work: Assessment of cardiac mass and function in patients with primary hyperoxaluria type I using MRI and non-conventional echocardiography.Methods: 22 patients diagnosed as PH type I following in Nephrology Unit, Cairo University Children{u2019}s Hospital underwent cardiac assessment using cardiac MRI and non-conventional echocardiography to assess LV mass and cardiac functions. Results: Patients with GFR less than 30 ml/min./1.73 m2 had greater LV mass and lower EF% than patients with GFR more than 30 ml/min./1.73 m2. By M-mode echocardiography, there are 2 patients (9%) with LV hypertrophy, while by 2D echo and CMR values are within the normal range. (A) wave peak velocity by pulsed wave Doppler was markedly high (mean 87.3 cm/s) in all patients denoting diastolic dysfunction.Conclusion: Patients with PH I have diastolic dysfunction, and LV mass increases with increased renal affection. Echocardiography overestimates LV mass compared to CMR
530 _aIssued also as CD
653 4 _aCardiac MRI
653 4 _aEcho cardiography
653 4 _aPrimary hyperoxaluria type I
700 0 _aMohammed Talaat Ali ,
_eSupervisor
700 0 _aSafaa Mohammed Abdalrahman ,
_eSupervisor
700 0 _aSoha Mohammed Mohammed Emam ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c68116
_d68116