000 | 02841cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223032112.0 | ||
008 | 181107s2018 ua d f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.08.03.Ph.D.2018.Mo.A | ||
100 | 0 | _aMohammed Ezzat Mohammed Draz | |
245 | 1 | 0 |
_aAnalytical study of some selected drugs containing nitrogen / _cMohammed Ezzat Mohammed Draz ; Supervised Hala Elsayed Zaazaa , Ahmed Sayed Saad , Adel Saber Lashien |
246 | 1 | 5 | _aدراسة تحليلة (تحليلية) لبعض الأدوية المختارة التي تحتوي على النيتروجين |
260 |
_aCairo : _bMohammed Ezzat Mohammed Draz , _c2018 |
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300 |
_a227 P. : _bcharts ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry | ||
520 | _aMulticomponent formulations have gained a lot of importance nowadays due to greater patient acceptability, increase potency, multiple action, and quick relief. Simultaneous estimation of drugs in combination is an important part in the field of pharmacy as it avoids time of extraction, separation and gets accurate and precise results. This concept was applied in some combinations of drugs used to treat nausea and vomiting in pregnancy like Pyridoxine HCl, Cyclizine HCl, and Meclozine HCl besides to Ritodrine HCl which used to arrest premature labor. Analysis of process-related impurities is very important in the pharmaceutical industry. The possibility of side and toxic effects, and reduced activity of the active substances must be reduced to a minimum. For this reason, different analytical techniques were developed for determination of the studied drugs in presence of their impurities. Aim of the work Development of rapid, economic, and selective methods for the analysis of the cited drugs in raw materials and in their pharmaceutical formulations without interference from their additives and impurities. Adoption as possible ecofriendly analytical methods as alternative to reported methods for determination of the studied drugs. Validation of the newly developed procedures according to ICH guidelines and application of the selected methods of analysis for determination of the studied drugs in their pharmaceutical dosage forms and biological fluids | ||
530 | _aIssued also as CD | ||
653 | 4 | _aCyclizine hydrochloride | |
653 | 4 | _aMeclozine hydrochloride | |
653 | 4 | _aPyridoxine hydrochloride | |
700 | 0 |
_aAdel Saber Lashien , _eSupervisor |
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700 | 0 |
_aAhmed Sayed Saad , _eSupervisor |
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700 | 0 |
_aHala Elsayed Zaazaa , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aEnas _eCataloger |
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905 |
_aNazla _eRevisor |
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942 |
_2ddc _cTH |
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999 |
_c68399 _d68399 |