000 02841cam a2200349 a 4500
003 EG-GiCUC
005 20250223032112.0
008 181107s2018 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.08.03.Ph.D.2018.Mo.A
100 0 _aMohammed Ezzat Mohammed Draz
245 1 0 _aAnalytical study of some selected drugs containing nitrogen /
_cMohammed Ezzat Mohammed Draz ; Supervised Hala Elsayed Zaazaa , Ahmed Sayed Saad , Adel Saber Lashien
246 1 5 _aدراسة تحليلة (تحليلية) لبعض الأدوية المختارة التي تحتوي على النيتروجين
260 _aCairo :
_bMohammed Ezzat Mohammed Draz ,
_c2018
300 _a227 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry
520 _aMulticomponent formulations have gained a lot of importance nowadays due to greater patient acceptability, increase potency, multiple action, and quick relief. Simultaneous estimation of drugs in combination is an important part in the field of pharmacy as it avoids time of extraction, separation and gets accurate and precise results. This concept was applied in some combinations of drugs used to treat nausea and vomiting in pregnancy like Pyridoxine HCl, Cyclizine HCl, and Meclozine HCl besides to Ritodrine HCl which used to arrest premature labor. Analysis of process-related impurities is very important in the pharmaceutical industry. The possibility of side and toxic effects, and reduced activity of the active substances must be reduced to a minimum. For this reason, different analytical techniques were developed for determination of the studied drugs in presence of their impurities. Aim of the work Development of rapid, economic, and selective methods for the analysis of the cited drugs in raw materials and in their pharmaceutical formulations without interference from their additives and impurities. Adoption as possible ecofriendly analytical methods as alternative to reported methods for determination of the studied drugs. Validation of the newly developed procedures according to ICH guidelines and application of the selected methods of analysis for determination of the studied drugs in their pharmaceutical dosage forms and biological fluids
530 _aIssued also as CD
653 4 _aCyclizine hydrochloride
653 4 _aMeclozine hydrochloride
653 4 _aPyridoxine hydrochloride
700 0 _aAdel Saber Lashien ,
_eSupervisor
700 0 _aAhmed Sayed Saad ,
_eSupervisor
700 0 _aHala Elsayed Zaazaa ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c68399
_d68399