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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.07.04.Ph.D.2018.Ab.E
100 0 _aAbeer Emad Mostafa Elansary
245 1 0 _aEffect of olive leaves extract on organs function of diabetic rats /
_cAbeer Emad Mostafa Elansary ; Supervised Abdelmoneim Mohamed Radwan Afify , Hossam Eldin Saad Elbeltagi , Sayed Abdelkader Fayed
246 1 5 _aتأثيرمستخلص أوراق الزيتون على وظائف الأعضاء بالجرذان المصابة بمرض السكر
260 _aCairo :
_bAbeer Emad Mostafa Elansary ,
_c2018
300 _a208 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Agriculture - Department of Agricultural Biochemistry
520 _aDiabetes mellitus is one of the most extensive diseases in the world. Olive tree leaves have been widely used in traditional therapies in European and Mediterranean countries as extracts, herbal teas, and powder. They contain numerous potentially bioactive compounds that may have hypoglycemic properties. Twenty-four adult Wistar rats were divided into four groups; (normal control), diabetic control (45 mg/kg STZ), normal rats treated with olive leaf extract (17.8 mg OLE /kg b.wt.), and diabetic rats treated with olive leaf extract (45 mg/kg STZ+ 17.8 mg OLE /kg b.wt.). Olive leaf extract was orally administrated for 10 weeks. The levels of serum iron, total iron binding capacity, ferritin, transferrin, hemoglobin, glycated hemoglobin, glycated albumin, GPX, SOD, GSH, CAT, MDA, lipid profile, heart function, Ü-amylase, glucose level, kidney and liver function were analyzed at zero time and after 10 weeks. Results showed that olive leaf extract significantly (P < 0.05) kept serum iron, total iron binding capacity in the normal range, and improved the ferritin, transferrin, and glycated hemoglobin and glycated albumin levels to make them less than the diabetic group levels. The OLE prevented the decrease of GSH and kept MDA around the normal range in the treated diabetic rats
530 _aIssued also as CD
653 4 _aIron
653 4 _aKidney function
653 4 _aLiver function
700 0 _aAbdelmoneim Mohamed Radwan Afify ,
_eSupervisor
700 0 _aHossam Eldin Saad Elbeltagi ,
_eSupervisor
700 0 _aSayed Abdelkader Fayed ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c69351
_d69351