000			03097cam a2200349 a 4500
003			EG-GiCUC
005			20250223032147.0
008			190112s2018 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aPh.D
099			_aCai01.11.07.Ph.D.2018.He.I
100	0		_aHeba Sherif Abdelaziz Fath Allah
245	1	0	_aImplementation of antibiotic policy and evaluation of antimicrobial stewardship program in an intensive care unit in cairo university specialized pediatric hospital / _cHeba Sherif Abdelaziz Fath Allah ; Supervised Mona Abdelaziz Wassef , Mona Mohiedden Abdelhalim , Amal Mohamed Sayed
246	1	5	_aتطبيق سياسة لاستخدام المضادات الحيوية مع تقييم برنامج يشمل وضع هذه السياسة و مراجعتها بوحدة عناية مركزة بمستشفى الأطفال التخصصى الجديد -اليابانى
260			_aCairo : _bHeba Sherif Abdelaziz Fath Allah , _c2018
300			_a142 P. : _bcharts ; _c25cm
502			_aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clincal and Chemical Pathology
520			_aBackground and objective: There is high antibiotics use in pediatric intensive care units (PICU) which could result into emergence of antibiotic resistance, spread of infections caused by multidrug resistant organisms, bad clinical outcome of patients, increase length of stay in hospitals, and increase drugs expenditure. The objective of this study was to set clinical practice guidelines customized according to local epidemiology of diseases and local cumulative antimicrobial susceptibility and implement ASP in the PICU and evaluate the ASP in optimizing antibiotics use, decreasing antibiotics expenditure, improving antimicrobial resistance patterns, decreasing patients{u2019} length of therapy and length of stay, and improving their clinical outcomes. Methods: A prospective study was conducted on a PICU in the Specialized Pediatric Hospital, Cairo University, to compare the pre-ASP implementation phase (April-September 2016) and the post-ASP implementation phase (January-June 2017). The antimicrobial stewardship team set facility-specific clinical practice guidelines and implemented the ASP through preauthorization and prospective-audit-with-feedback. Then the ASP was evaluated through measuring adherence of physicians to the guidelines, ASP interventions and recommendations and acceptance of them, the overall rate of mortality, length of stay (LOS), drug costs, antibiotics days of therapy (DOT), and length of therapy (LOT)
530			_aIssued also as CD
653		4	_aAntibiotic Use
653		4	_aAntimicrobial stewardship program
653		4	_aPediatric antimicrobial stewardship
700	0		_aAmal Mohamed Sayed , _eSupervisor
700	0		_aMona Abdelaziz Wassef , _eSupervisor
700	0		_aMona Mohiedden Abdelhalim , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c69514 _d69514