| 000 | 02759cam a2200325 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 008 | 190211s2018 ua f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.10.10.Ph.D.2018.Fa.P | ||
| 100 | 0 | _aFatma Fathy Ibrahim Hassan | |
| 245 | 1 | 0 |
_aPreparation and evaluation of a combined bivalent vaccine against avian pasteurella and mycoplasma infections in chickens / _cFatma Fathy Ibrahim Hassan ; Supervised Mahmoud Essam Hatem Ahmed , Jakeen Kamal Eljakee , Wafaa Abdelghany Abdelghany |
| 246 | 1 | 5 | _aتحضير وتقييم لقاح مشترك ثنائى ضد عدوى الباستريلا والميكوبلازما فى الدجاج |
| 260 |
_aCairo : _bFatma Fathy Ibrahim Hassan , _c2018 |
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| 300 |
_a136 P. ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology | ||
| 520 | _aThe present work was planned to study the immune response of chickens vaccinated with locally prepared combined inactivated vaccine of M. gallisepticum and P. multocida adjuvanted with Montanide ISA70. 150, 4 weeks old specific pathogen free chickens were divided into five groups, the 1st group was vaccinated with P. multocida vaccine, the 2nd group was vaccinated with M. gallisepticum vaccine, the 3rd group was vaccinated with combined M. gallisepticum and P. multocida vaccine, the 4th group was vaccinated with imported M. gallisepticum vaccine and the 5th group was kept unvaccinated as a control group. The prepared vaccines were evaluated by determination of the cellular immunity by heterophils/lymphocytes ratio and measurement of nitric oxide in the supernatant of macrophage, and evaluation of the humoral immunity by indirect haemagglutination, haemagglutination inhibition and ELISA techniques.The potency of the vaccines were evaluated by the challenge and passive mouse protection tests against the challenge with the virulent strain of M. gallisepticum (Eis3-10 strain) and P. multocida (serotypes A and D). The results showed that combined inactivated vaccine of M. gallisepticum and P. multocida adjuvanted with Montanide ISA70 induced high and long duration of antibody response and significant protection against the challenge with virulent strain of M. gallisepticum (Eis3-10 strain) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aInactivated vaccine | |
| 653 | 4 | _aM. gallisepticum | |
| 653 | 4 | _aP. multocida | |
| 700 | 0 |
_aJakeen Kamal Eljakee , _eSupervisor |
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| 700 | 0 |
_aMahmoud Essam Hatem Ahmed , _eSupervisor |
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| 700 | 0 |
_aWafaa Abdelghany Abdelghany , _eSupervisor |
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_aNazla _eRevisor |
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_aShimaa _eCataloger |
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_2ddc _cTH |
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_c70098 _d70098 |
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