000 01899cam a2200313 a 4500
003 EG-GiCUC
008 190211s2018 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.10.10.Ph.D.2018.Al.I
100 0 _aAliaa Abdelbakey Mohamed Abdelbakey
245 1 0 _aImmunological studies of C. perfringens type "A" using nanotechnology /
_cAliaa Abdelbakey Mohamed Abdelbakey ; Supervised Mona Ibrahim Hassan Elenbaawy , Hamed Adel Hamed Elhelw
246 1 5 _aدراسات مناعية علي لقاح الكلوسترديم بيرفرينجنز نوع "أ" باستخدام تقنية النانو
260 _aCairo :
_bAliaa Abdelbakey Mohamed Abdelbakey ,
_c2018
300 _a92 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Veterinary Medicine - Department of Microbiology
520 _aClostridium perfringens type A has a great impact in rabbit farms due to great loses and high mortalities specially among weaned rabbits, it causes severe diarrhea, bloat and enterotoxaemia. In the present work, C. perfringens alpha toxoid vaccine adjuvanted by either aluminum hydroxide gel and poly lactide co-Glycolic acid (PLGA) nanoparticles was prepared. It was revealed that enterotoxaemia and bloat vaccine adjuvanted by aluminum hydroxide gel in 2 doses protect rabbits for 6 months, while the vaccine adjuvanted by PLGA nanoparticles protect rabbits for 10 months after one shot of administration
530 _aIssued also as CD
653 4 _aC. perfringens
653 4 _aNanoparticles
653 4 _aPoly-L-lactide-co-glycolidic acid PLGA
700 0 _aHamed Adel Hamed Elhelw ,
_eSupervisor
700 0 _aMona Ibrahim Hassan Elenbaawy ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c70115
_d70115