000			03011cam a2200349 a 4500
003			EG-GiCUC
005			20250223032205.0
008			190213s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2018.Fa.C
100	0		_aFatma Abdelaziz Khalifa
245	1	0	_aClinical characteristics, neuroimaging and outcome of acute disseminated encephalomyelitis in children / _cFatma Abdelaziz Khalifa ; Suprervised Mervat Haroon , Marian Yousri Fahmy , Rania Hamdy
246	1	5	_aالاعراض الاكلينيكيه والاشعه العصبيه والنتائج في مرض الالتهاب الدماغي الحاد المتناثر في الاطفال
260			_aCairo : _bFatma Abdelaziz Khalifa , _c2018
300			_a133 P. : _bcahrts , facsimiles ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aIntroduction Acute disseminated encephalomyelitis (ADEM) is an immune mediated disease of the brain. Although it occurs in all ages, most reported cases are in children and adolescents.The aim of this study was to assess the clinical characterization, neuroimaging and outcome of ADEM in children in Pediatric Hospital of Cairo University. Methods This observational study was carried out from January 2016 to December 2016 in the Pediateric Hospital of Cairo University. All children diagnosed as ADEM during a one year period were included in the study. All studied cases were followed up and reevaluated at three months . we use SPSS version 22 and Chi square, t{u2012}test for data analysis. Results Twenty children were included in this study (12 male and 8 female), the average age was 4.6 +3.2 years. Prodroma was found in 55% of the cases while the commonest presentation were motor defecits (as ataxia, paraparesis, hemiparesis and monoparesis), convulsions (either generalized or focal or even status epilepticus) and altered consciousness. Demyelination patches were multifocal In 80%, mainly subcortical white matter lesions which were bilateral and asymmetric in location and size. Assessment after 3 months follow up showed 55% full recovery, 25% were cured with remaining neurological defecits,15% relapse and 5% death. The predictors of better outcome were children with higher GCS (6{u2012}14) (p=0.023 ) Conclusion The clinical pattern of Acute disseminated encephalomyelitis is variable and motor defecits was the common presentation. The outcome is generaly favorable
530			_aIssued also as CD
653		4	_aAcute disseminated encephalomyelitis (ADEM)
653		4	_aCharacteristics
653		4	_aNeuroimaging
700	0		_aMarian Yousri Fahmy , _eSupervisor
700	0		_aMervat Haroon , _eSupervisor
700	0		_aRania Hamdy , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c70144 _d70144