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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.05.M.Sc.2018.Wa.R
100 0 _aWalaa Ahmed Alkady
245 1 0 _aRetrospective study of infectious complications of pediatric patients with acute lymphoblastic leukemia during maintenance therapy /
_cWalaa Ahmed Alkady ; Supervised Emad Nabil Ebeid , Hadeer Ahmad Elmahalawy , Youssef Madney Saeed
246 1 5 _aدراسه استرجاعية لتأثير مضاعفات العدوى لدى مرضى سرطان الدم الليمفاوي الحاد في الأطفال أثناء فترة العلاج المستمر
260 _aCairo :
_bWalaa Ahmed Alkady ,
_c2018
300 _a146 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520 _aBackground: Infectious complications are a serious cause of morbidity and mortality in cancer patients especially those with hematological malignancies. Decrease the risk of serious and long lasting infections need detailed information about the frequency and characteristic features of infections. Objective: To assess epidemiology of infectious episodes and to evaluate infection related mortality during maintenance phase of chemotherapy. Patients and methods: Retrospective cohort study of infectious complications for ALL pediatric patients who treated at NCI during the period from June 2011 to December 2014. Results: A total of 1052 infectious episodes recorded in 146/152 ALL pediatric patients during maintenance chemotherapy with an average of 7 episodes/ patient and a range of 0-26 episodes/patient. FUO was the most common infectious episodes (36.8%) followed by clinically documented infections (26%), viral (17%), bacterial (16.8%) and fungal infections (3.6%). Most of infectious episodes 412/1052 (39.16%) occurred during early phase of maintenance chemotherapy w (1-19). Standard and high risk group reported 609/1052 (58%) infectious episode of which (44%) reported during early phase, in comparison to low risk group reported 433/1052 (41.2%) infectious episode, of which (33%) episodes reported during the early phase
530 _aIssued also as CD
653 4 _aAcute lymphoblastic leukemia
653 4 _aInfections
653 4 _aMaintenance
700 0 _aEmad Nabil Ebeid ,
_eSupervisor
700 0 _aHadeer Ahmad Elmahalawy ,
_eSupervisor
700 0 _aYoussef Madney Saeed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c70601
_d70601