| 000 | 02408cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032226.0 | ||
| 008 | 190313s2018 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.12.21.M.Sc.2018.Do.H | ||
| 100 | 0 | _aDoha Hanafy Mahmoud | |
| 245 | 1 | 0 |
_aHistopathological evaluation of fetuses of rats treated with anti-emetic domperidone during pregnancy / _cDoha Hanafy Mahmoud ; Supervised Rashika Hussin Mostafa , Heba Ali Abdelrahman |
| 246 | 1 | 5 | _aالتقيم الهستوباثولوجى لأجنة وولائد الجرذان البيضاء المعالجة بمضاد القىء دومبريدون اثناء الحمل |
| 260 |
_aCairo : _bDoha Hanafy Mahmoud , _c2018 |
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| 300 |
_a113 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology | ||
| 520 | _aDrugs play an important role in improving human health and promoting well-being.The state of pregnancy requires that all medications should be prescribed with specific caution. Nausea and vomiting are the most common symptoms of pregnancy. Nausea and vomiting of pregnancy (NVP) affects up to 85% of all pregnancies. Treatment of NVP included several routes one of them was antiemetic medication (domperidone). In this study we aimed to investigate the potential effect of domperidone on the pregnancy outcomes and embryos.The study was done using pregnant albino rats (Rattus norvegicus) which treated during organogenesis period with therapeutic dose of the chosen drug. At 20th gestational day all the animals were sacrificed under anesthesia and fetuses with their placentas were removed from the uterus and evaluated for mortality rate, growth parameters,morphological and skeletal malformation also histological study of placenta, fetal liver, kidney and brain.The results revealed a significant decrease in the all growth parameters, high incidence of resorption in treated animals | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAntiemetic | |
| 653 | 4 | _aDomperidone | |
| 653 | 4 | _aPregnancy | |
| 700 | 0 |
_aHeba Ali Abdelrahman , _eSupervisor |
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| 700 | 0 |
_aRashika Hussin Mostafa , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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_aShimaa _eCataloger |
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_2ddc _cTH |
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_c70827 _d70827 |
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