| 000 | 02595cam a2200325 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 008 | 190314s2018 ua f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.11.23.M.Sc.2018.Na.R | ||
| 100 | 0 | _aNafie Faisal Mohamed Makady | |
| 245 | 1 | 0 |
_aRetrospective study of extranodal non-hodgkin{u2019}s lymphoma : _bResponse to treatment and factors affecting prognosis / _cNafie Faisal Mohamed Makady ; Supervised Ehab Mostafa Elnakoury , Raafat Ragai Abdelmalek , Mennat Allah Mahmoud Mohamed |
| 246 | 1 | 5 |
_aدراسة مرجعية عن ورم الغدد الليمفاوية (اكسترانودال) خارج الغدد الليمفاوية : _bالاستجابة للعلاج و العوامل المؤثرة فى مسار المرض |
| 260 |
_aCairo : _bNafie Faisal Mohamed Makady , _c2018 |
||
| 300 |
_a91 P. ; _c25cm |
||
| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Oncology-Clinical | ||
| 520 | _aThis is a 10-year retrospective study on patients diagnosed with aggressive lymphoma in NEMROCK between 2008-2018. We investigated the effect of extranodal involvement and its effect on response and survival. Data of patients with aggressive lymphoma was collected from the NEMROCK database and analyzed. Out of 377 patients, 210 (55.7%) patients had extranodal involvement. The most common site involved was GIT followed by head and neck. Our study confirms that patients with extranodal involvement show worse OS, especially with GIT, bone marrow, skin/soft tissue, and CNS involvement. There was no significant difference in DFS between nodal and extranodal involvement. There was significant difference in response rate between nodal and extranodal group of patients after treatment with chemotherapy. This significant difference was eliminated after addition of rituximab to chemotherapy. Patients with bulky lymph nodes (>7.5 cm) showed significantly worse response rates and survival. Only 4.9% of patients developed CNS relapse. Our results showed that there is significant association between extranodal involvement of the head/neck and skin/soft tissue with CNS relapse | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aExtranodal | |
| 653 | 4 | _aLymphoma | |
| 653 | 4 | _aNon-Hodgkin | |
| 700 | 0 |
_aEhab Mostafa Elnakoury , _eSupervisor |
|
| 700 | 0 |
_aMennat Allah Mahmoud Mohamed , _eSupervisor |
|
| 700 | 0 |
_aRaafat Ragai Abdelmalek , _eSupervisor |
|
| 905 |
_aNazla _eRevisor |
||
| 905 |
_aSamia _eCataloger |
||
| 942 |
_2ddc _cTH |
||
| 999 |
_c70837 _d70837 |
||