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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2018.Am.S
100 0 _aAmira Ahmed Gad
245 1 0 _aSepsis profile, antibiotics given and outcomes of preterm neonates admitted in Kasr Al-Ainy Neonatal intensive care unit (NICU) /
_cAmira Ahmed Gad ; Supervised Khaled Mohamed Salama , May Mohamed Sherif , Sarah Samir Eltatawy
246 1 5 _aمعاملات الالتهابات البكتيرية و المضادات الحيوية المستخدمة و النتائج لحالات الخدج المصابين بتسمم الدم بوحدة رعاية الاطفال حديثي الولادة بمستشفى القصر العيني ، جامعة القاهرة
260 _aCairo :
_bAmira Ahmed Gad ,
_c2018
300 _a114 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aIntroduction : Globally, sepsis is still one of the major causes of morbidity and mortality in neonates, in spite of recent advances in health care units. Objectives: This study aimed at studying risk factors and outcomes of neonatal sepsis in preterm infants, determining the efficacy of using hematological scoring system in diagnosis of sepsis and detecting common bacterial organisms in Neonatal intensive care unit (NICU) environment.Methods: The study included 153 cases of preterm neonates with suspected sepsis, admitted in Kasr Al-Ainy NICU over a period of 12 months. We studied the impact of different parameters on outcome, antibiograms and the value of blood culture in diagnosis of sepsis. In addition, we tested the efficacy of hematological score of Rodwell in detection of sepsis in culture-proven cases.Results: Late-onset sepsis cases were more common than early-onset sepsis (58.8% versus 41.2%) with better survival rates (57.8% versus 38.1%). Culture-positive cases represented 39.8% only. Klebsiella MDR was the most common organism in early-onset sepsis versus CONS in late-onset sepsis. All bacterial organisms showed high resistance against Amoxicillin-clavulanic, Gentamicin and Carbapenems (first and second lines of antibiotics used). Hematological score of Rodwell showed significant p-value (0.017) in association with culture-proven sepsis cases. Immature: mature PMNs ratio had the highest sensitivity (85.7%), high specificity (78.9%), PPV (80.5%) and NPV (84.5%)
530 _aIssued also as CD
653 4 _aBlood culture
653 4 _aNeonatal sepsis
653 4 _aPrematurity
700 0 _aKhaled Mohamed Salama ,
_eSupervisor
700 0 _aMay Mohamed Sherif ,
_eSupervisor
700 0 _aSarah Samir Eltatawy ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aEnas
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c71559
_d71559