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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.12.04.Ph.D.2018.Hi.I
100 0 _aHisham Ali Hammed Elshoky
245 1 0 _aIn vitro localization of nanomaterials using biophysics techniques for biological evaluation /
_cHisham Ali Hammed Elshoky ; Supervised Mohamed Hassanin Gaber , Maha Anwar Ali , Taher Ahmed Salah Eldin
246 1 5 _aتحديد مواقع المواد النانومترية معمليا باستخدام تقنيات فيزيائية حيوية للتقييم البيولوجى
260 _aCairo :
_bHisham Ali Hammed Elshoky ,
_c2018
300 _a125 P. :
_bcharts , facsimiles , photographs ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biophysics
520 _aNanotechnology covers all fields and is applied in industrials, biological and environmental areas. Nanoparticles have several application, such as gene and drug delivery, due to their biocompatibility. We have chosen to synthesis and asses gold (GNPs), chitosan (CS), graphene oxids (GO) and zinc oxide (ZnO) nanoparticles to represent totally different sorts on nanomaterials. Nanoparticles are currently produced by wet chemistry, humers' modified method, ionic gelation method, and the sol-gel method. Here, we synthesized and characterized GNPs, GO, CS, ascorbate CS (AsCS) and ZnO nanoparticles and modified forms of ZnO and investigated their cytotoxic effects, intemalization, and distribution within the human colon carcinoma cell line using confocal laser scanning microscopy CLSM. GNPs and GO show biocompatibility at high concentration and when inter cells it does not enter the nucleus because of the size of the sheets of GO and GNPs encompasses a negative charge
530 _aIssued also as CD
653 4 _aCytotoxicity
653 4 _aLocalization
653 4 _aNanoparticles
700 0 _aMaha Anwar Ali ,
_eSupervisor
700 0 _aMohamed Hassanin Gaber ,
_eSupervisor
700 0 _aTaher Ahmed Salah Eldin ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c71570
_d71570