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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.09.12.M.Sc.2018.Lo.R
100 0 _aLobna Mohamed Salah Eldin Abdellatif
245 1 0 _aRegenerative potential of microvesicles versus bone marrow stem cells in treating irradiated parotid salivary glands of albino rats :
_b An animal study /
_cLobna Mohamed Salah Eldin Abdellatif :
_ban animal study ; Supervised Manal Elassaly , Dalia Elbaz , Laila Rashed
246 1 5 _aدراسة التأثير العلاجي بالحويصلات الصغيرة مقارنة بالخلايا الجذعيه لنخاع العظم علي الغدد النكافيه المعرضه للإشعاع :
_bدراسة على الحيوان
260 _aCairo :
_bLobna Mohamed Salah Eldin Abdellatif ,
_c2018
300 _a139 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral Biology
520 _aThe present work aimed to assess the possible regenerative potential of Microvesicles versus Bone marrow mesenchymal stem cells on parotid glands of irradiated albino rats. The study was carried out on forty eight adult healthy male albino rats weighing about 200-250 grams. The animals were classified into three main equal groups of 16 rats. All the rats were subjected to a dose of radiation of 10 Gy. The rats of group A received no treatment after irradiation. Rats of group B recieved a single dose of 1{u00D7}106 cells/mL of BMSCs injected intravenously, immediately after irradiation. Whereas, the rats of group C received a single intravenous injection of 30 og of BMSCs derived MVs immediately after irradiation.The animals were fed the normal laboratory diet ad libitum throughout the experimental period. At the end of the experiment, the animals were sacrificed and the parotid glands were dissected out and processed to be embedded in paraffin wax. Sections of five microns were cut and mounted on glass slides to be stained with H&E for histopathological study. For immunohistochemical examination, the paraffin sections were mounted on positively charged microscopic glass slides for evaluation of expression of epidermal growth factor receptor (EGFr)
530 _aIssued also as CD
653 4 _aCell-derived microparticles
653 4 _aRadiotherapy
653 4 _aStem cells
700 0 _aDalia Elbaz ,
_eSupervisor
700 0 _aLaila Rashed ,
_eSupervisor
700 0 _aManal Elassaly ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c71647
_d71647