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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.05.M.Sc.2018.Sa.P
100 0 _aSally Mahfouz Abdelnaby
245 1 4 _aThe prognostic value of Interim PET in pediatric hodgkin lymphoma, National cancer institute, Egypt 2011-2015 /
_cSally Mahfouz Abdelnaby ; Supervised Lobna Mohammed Shalaby , Reham Abdelaziz Khedr , Hoda Fathy Elsayed
246 1 5 _aكمؤسر فى علاج سرطان الأطفال الليمفاوى هودجيكن بالمعهد القومى لللاورام: مصر 2011-2015 PET CT تقييم استخدام المسح الذرى
260 _aCairo :
_bSally Mahfouz Abdelnaby ,
_c2018
300 _a103 P. :
_bcharts ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520 _aBackground: Hodgkin's lymphoma (HL) is a highly curable malignant disease. Risk-adapted therapy for children with HL is directed toward high survival, minimal toxicity and optimal quality of life. 18F-FDG PET is a well-established surrogate for tumor chemosensitivity early during therapy. The ongoing PET-adaptive clinical trials are testing the hypothesis that a decision can reliably be made on escalating or deescalating therapy based on interim PET results. Aims: In this study we aimed to identify the prognostic role of interim PET in predicting the prognosis of HL in our center. Methods: This is a retrospective, single center study where a total of 140 patients with newly diagnosed Hodgkin lymphoma were enrolled. Only 83 patients were eligible for analysis of interim PET. PET scan was performed at baseline and after two cycles of chemotherapy. Treatment was not changed according to the results of the interim scan. PET scans reports was used using the Deauville five-point scale, blinded to treatment outcome
530 _aIssued also as CD
653 4 _aChildhood
653 4 _aHodgkin's lymphoma
653 4 _aPET
700 0 _aHoda Fathy Elsayed ,
_eSupervisor
700 0 _aLobna Mohammed Shalaby ,
_eSupervisor
700 0 _aReham Abdelaziz Khedr ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c71785
_d71785