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003 EG-GiCUC
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008 190519s2018 ua o f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.08.09.M.Sc.2018.Mo.R
100 0 _aMona Mohammed Abdelhamid Elkashoury
245 1 0 _aRole of certain natural products on blood coagulation in streptozotocin-induced diabetes in irradiated rats /
_cMona Mohammed Abdelhamid Elkashoury ; Supervised Ezzeddin S. M. Eldenshary , Laila A. A. Ramadan , Ashraf K. A. Bahgat
246 1 5 _aدور بعض المنتجات الطبيعية على تجلط الدم فى مرض السكر المحدث بالاستربتوزوتوسن فى الجرذان المشععة
260 _aCairo :
_bMona Mohammed Abdelhamid Elkashoury ,
_c2018
300 _a270 P. :
_bphotographs ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology
520 _aThe present study was conducted to evaluate the role of yeast beta glucan or vitamin E on oxidative stress, clotting, haematological and biochemical abnormalities in gamma / irradiated, diabetic and diabetic gamma / irradiated rats. In order to achieve the goal of the present study, plasma glucose level, body weight, pancreas weight, oxidative stress parameters included plasma malondialdehyde and blood glutathione, clotting factors included platelet aggregation, prothrombin time and activated partial thromboplastin time, complete blood count and lipid profile were measured. Exposure to fractionated gamma / irradiation didn't affect the plasma glucose level and body weight, increased pancreas weight, plasma MDA, MPV, PDW, PT, APTT and LP relatively with its components and decreased blood GSH, PA, PC and CBC relatively with its components. Exposure to fractionated gamma / irradiation or induction of diabetes followed by exposure to fractionated gamma / irradiation followed by administration of yeast beta glucan or vitamin E to both of them didn't affect the plasma glucose level and body weight and increased pancreas weight, blood GSH, PC, PT, APTT and CBC relatively with its components and decreased plasma MDA, PA, MPV, PDW and LP relatively with its components
530 _aIssued also as CD
653 4 _aGamma / irradiation
653 4 _aVitamin E
653 4 _aYeast beta glucan
700 0 _aAshraf Kamal Abdelmaged Bahgat ,
_eSupervisor
700 0 _aEzzeddin Saeed Mohamed Eldenshary ,
_eSupervisor
700 0 _aLaila Ahmed Abdelaziz Ramadan ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aSamia
_eCataloger
942 _2ddc
_cTH
999 _c72041
_d72041