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008 190624s2018 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.07.Ph.D.2018.La.R
100 0 _aLamyaa Hany Abdellatif Soliman
245 1 0 _aRole of apelin in the pathophysiology of esophageal varices complicating chronic HCV infection in Egyptian patients /
_cLamyaa Hany Abdellatif Soliman ; Supervised Iman Refaat Elmahgoub , Rania Ahmed Zayed , Fadwa Saied Abdelazim
246 1 5 _aدور الابلين في الفيسيولوجية المرضية لدوالي المريء في مرضى الالتهاب الكبدي الوبائي سي المصريين
260 _aCairo :
_bLamyaa Hany Abdellatif Soliman ,
_c2018
300 _a150 P. :
_bcharts ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
520 _aIntroduction and aim of work: Portal hypertension and esophageal varices formation complicating chronic HCV infection are considered the most devastating side effects of chronic liver disease owing to the bleeding-related mortality. Angiogenesis is the hallmark of their pathogenesis. Apelin is one of the recently identified angiogenic and fibrogenic peptide of wide distribution in various tissues. We studied apelin gene expression and SNP (rs3761581) of the apelin gene in chronic HCV patients to assess their association with the degree of hepatic fibrosis, esophageal varices formation as well as the grade of esophageal varices
530 _aIssued also as CD
653 4 _aaAngiogenesis
653 4 _aApelin
653 4 _aHepatitis C
700 0 _aFadwa Saied Abdelazim ,
_eSupervisor
700 0 _aIman Refaat Elmahgoub ,
_eSupervisor
700 0 _aRania Ahmed Zayed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAsmaa
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c72554
_d72554