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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.19.M.Sc.2018.Sh.B
100 0 _aShaimaa Mohamed Elsayed Seleim
245 1 0 _aBiofilm formation by acinetobacter species isolated from intensive care units of Kasr Alainy University hospitals and its impact on antibiotic resistance /
_cShaimaa Mohamed Elsayed Seleim ; Supervised Mona Abdelwahab Abdelmassih , Mohamed Hamdy Mohamed Saleh , Doaa Mahdy Mohamed Elwakil
246 1 5 _aتكوين الغشاء الحيوى لفصائل الأسينيتوباكتر المعزولة من وحدات العناية المركزة بمستشفيات القصر العيني الجامعي وتأثيره على مقاومة الميكروب للمضادات الحيوية
260 _aCairo :
_bShaimaa Mohamed Elsayed Seleim ,
_c2018
300 _a112 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Microbiology and Immunology
520 _aAcinetobacter spp. are important clinical pathogens and are considered as one of the major causes of healthcare-associated pneumonia, bacteremia, UTI and wound infections. Unfortunately, the treatment of Acinetobacter infections is becoming more difficult because nosocomial isolates are increasingly resistant to commonly used antimicrobial agents.The potential ability of Acinetobacter to form biofilm might explain its outstanding antibiotic resistance, survival properties and increased virulence. The aim of the present study was to detect the biofilm formation by Acinetobacter isolates and their antibiotic resistance pattern. In addition, it attempted to investigate the impact of biofilm formation on antibiotic resistance.A total of 50 isolates of Acinetobacter, recovered from patients admitted to ICUs, were collected from laboratories of Kasr Al-Ainy University hospitals. The isolates were recovered from different clinical samples, then subcultured on MacConkey{u2019}s medium and identified by conventional microbiological methods. Antibiotic susceptibility testing was performed by Kirby- Bauer disk diffusion method and for polymyxin, broth microdilution method was used.The ability of Acinetobacter spp. to produce biofilm was determined using tissue culture plate method. Acinetobacter isolates were most frequently recovered from respiratory samples (54%)
530 _aIssued also as CD
653 4 _aAcinetobacter
653 4 _aAntibiotic resistance
653 4 _aBiofilm
700 0 _aDoaa Mahdy Mohamed Elwakil ,
_eSupervisor
700 0 _aMohamed Hamdy Mohamed Saleh ,
_eSupervisor
700 0 _aMona Abdelwahab Abdelmassih ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c72566
_d72566