| 000 | 02441cam a2200325 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 008 | 190629s2018 ua f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.19.04.M.Sc.2018.Ba.E | ||
| 100 | 0 | _aBasma Ferhad Fakieh Abdou | |
| 245 | 1 | 0 |
_aEvaluation of glypican 3 and vascular endothelial growth factor as a biomarkers and their clinico-pathologic significance in hepatocellular carcinoma cases / _cBasma Ferhad Fakieh Abdou ; Supervised Osman Mohammed Mansour , Mohammed Ali Saber , Amira Hanafi Soliman |
| 246 | 1 | 5 | _a بمثابة المؤشرات الحيوية و كذلك الأهمية الإكلينيكية والباثولوجية لهم في مرضي سرطان الكبد في معهد الأورام القومى- مصر (GPC3 and VEGF) تقييم |
| 260 |
_aCairo : _bBasma Ferhad Fakieh Abdou , _c2018 |
||
| 300 |
_a229 P. ; _c25cm |
||
| 502 | _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) | ||
| 520 | _aBackground: Hepatocellular carcinoma (HCC) is a major health problem with doubling in incidence rates in Egypt in the past 10 years.It represents the most common primary malignant tumor of the liver and one of the major causes of death.Early detection of Hepatocellular Carcinoma enhances effective and curative management. Glypican 3 is an oncofetal protein that only detected in HCC not in normal liver,while VEGF is one of the most important angiogenesis regulators and its overexpression has been reported in HCC. Aim of the study:is to assess the clinical utility of serum GPC3 and VEGF for the diagnosis of HCC. Patients and Methods:this study included 40 patients with HCC, 40 patients with Liver Cirrhosis as benign control group and 10 apparently healthy volunteers as normal controls. All cases were subjected to routine laboratory investigations, measurement of serum GPC3 and VEGF using ELISA, in addition GPC3 and VEGF mRNAs using RT-PCR, in peripheral blood samples | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aGlypican 3 | |
| 653 | 4 | _aHepatocellular carcinoma | |
| 653 | 4 | _aVEGF | |
| 700 | 0 |
_aAmira Hanafi Soliman , _eSupervisor |
|
| 700 | 0 |
_aMohammed Ali Saber , _eSupervisor |
|
| 700 | 0 |
_aOsman Mohammed Mansour , _eSupervisor |
|
| 905 |
_aNazla _eRevisor |
||
| 905 |
_aShimaa _eCataloger |
||
| 942 |
_2ddc _cTH |
||
| 999 |
_c72595 _d72595 |
||