000			02763cam a2200337 a 4500
003			EG-GiCUC
005			20250223032321.0
008			190703s2018 ua dh f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.11.28.M.Sc.2018.Es.R
100	0		_aEslam Mohamed Elsaeed
245	1	0	_aRole of speckle tracking echocardiography in detection of subtle systolic myocardial dysfunction in familial Mediterranean fever patients / _cEslam Mohamed Elsaeed ; Supervised Azza Abdelkadder Ali Elhamshary , Antoine Fakhry Abdelmassih
246	1	5	_aدور التتبع الجزئي بالموجات الصوتيه لتشخيص الاعتلال الانقباضي لمقمب بمرضى حمى البحر الأبيض المتوسط
260			_aCairo : _bEslam Mohamed Elsaeed , _c2018
300			_a91 P. : _bcharts , facsimiles ; _c25cm
502			_aThesis (M.Sc) - Cairo University - Faculty of Medicine - Department of Pediatrics
520			_aIntroduction: Familial Mediterranean fever (FMF) is the most common of the auto-inflammatory syndromes and is the most frequent periodic fever syndrome. It is important to early recognizing cardiovascular involvements as some of them are associated with increased morbidities and mortality. The aim of the study is to detect subtle systolic myocardial dysfunction in FMF patients by 2D STE. Methods: Forty- six Egyptian children diagnosed as having FMF and in attack-free period, were included in the study together with forty-six healthy children, age and sex- matched. Patients have been recruited from pediatric rheumatology clinics in Cairo University. Conventional and 2D STE was performed to all patients and control subjects. Results: Though no statistically significant difference was noted between cases and controls by conventional echocardiographic parameters, compared to normal subjects, FMF patients had a statistical significant reduction of both left ventricular global longitudinal strain (- 18.3 ± 5.5 % vs -23.9 ± 1.4 % ,p<0.0001) and left ventricular circumferential strain (-10.5 ± 2.1% vs -20 ± 2% ,p <0.0001). GLS was significantly correlated with genotype of FMF patients. Conclusions: 2D derived GLS and GCS proves to be promising tools for early detection of subtle myocardial injury in FMF patients
530			_aIssued also as CD
653		4	_a2D-STE
653		4	_aFamilial Mediterranean fever
653		4	_aSubtle myocardial dysfunction
700	0		_aAntoine Fakhry Abdelmassih , _eSupervisor
700	0		_aAzza Abdelkadder Ali Elhamshary , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c72639 _d72639