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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2019.Sa.N
100 0 _aSamar Ahmed Ashry Mohamed
245 1 0 _aNitrous oxide level in neonates with pulmonary hypertension /
_cSamar Ahmed Ashry Mohamed ; Supervised Walaa Alsharany Abuelhamd , Antoine Fakhry Abdelmassih , Marianne Edward Gad Elkarim
246 1 5 _aمستوى أكسيد النيتروز في الأطفال حديثي الولادة المصابين باعتلال ارتفاع ضغط الشريان الرئوي
260 _aCairo :
_bSamar Ahmed Ashry Mohamed ,
_c2019
300 _a185 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a cardiopulmonary disorder of near term and term neonates characterized by elevated pulmonary vascular resistance with shunting of pulmonary blood to systemic circulation results in significant hypoxemia .It can occur as a primary idiopathic or secondary to maternal and fetal factors. Inhaled NO (iNO) is main line of treatment.Decreased endogenous nitric oxide (NO) synthesis play a role in the etiopathogenesis of PPHN on the other side in hypoxic ischemic encephalopathy (HIE) there is activation of neuronal nitric oxide synthase and generation of NO.Aim of work: detection of serum level of endogenous NO in term and near term neonates with PPHN either associated with birth asphyxia or not and its relation to outcome.patients and methods: case- control study was conducted in the period from July 2018 till the end of November 2018 as 40 neonate with PPHN(20 primary non asphyxiated and 20 secondary asphyxiated)were admitted at Cairo University Hospital NICU compared to 40 healthy neonate using history taking, examination ,echocardiography, labs ,serum NO level and follow up
530 _aIssued also as CD
653 4 _aAsphyxia
653 4 _aNeonates
653 4 _aNO
700 0 _aAntoine Fakhry Abdelmassih ,
_eSupervisor
700 0 _aMarianne Edward Gad Elkarim ,
_eSupervisor
700 0 _aWalaa Alsharany Abuelhamd ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c73190
_d73190