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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.10.M.Sc.2019.Mo.E
100 0 _aMona Raghib Ali Elmessary
245 1 0 _aEfficacy of adding oral zinc to intralesional MMR vaccine or electrosurgery for common warts :
_bA comparative clinical study /
_cMona Raghib Ali Elmessary ; Supervised Marwa Safwat Elhawary , Ahmed Mohammed Nada , Sarah Ibrahim Ismail
246 1 5 _aقدار كفاءة اضافة الزنك عن طريق الفم الى الحقن الموضعي لمصل (النكاف و الحصبه و الحصبه الالماني) أو الى الكي الكهربائي لعلاج الثآليل الفيروسيه الشائعه :
_bدراسه سريريه مقارنه
260 _aCairo :
_bMona Raghib Ali Elmessary ,
_c2019
300 _a85 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology
520 _aBackground:Several treatment options exist for warts. Destructive approaches ''although the most common'' are sometimes inconvenient especially for large and multiple warts, leaving wide areas of raw skin that takes time to heal with increased liability to infection.Thus, immunotherapy emerged as a better treatment option for resistant warts.Various agents have been used for enhancing the immune response, including oral zinc, interferons, H2 receptor blockers, intralesional injection of MMR vaccine, Candida antigen, PPD and BCG. Imiquimod and DPC have shown efficacy, as well.Both arms of adaptive immunity, cell mediated and humoral immune systems appear to be influenced by zinc. It is expected to promote Th1 cytokine response with further activation of cytotoxic T cells and natural killer cells, subsequently eradicating HPV infected cells. Aim of work:To assess whether adding oral zinc to either intralesional MMR or electrosurgery of single targeted wart would enhance a therapeutic response in distant warts. Patient and Methods:40 patients with multiple common warts were first tested for existing immunity.Twenty patients with positive sensitivity test were enrolled into either of theIL MMR groups; ILMMR group (A) or ILMMR with oral zinc group (B). The other twenty patients were allocated into either of electrosurgery groups; electrosurgery of a single wart (C) or electrosurgery of a single wart with oral zinc (D)
530 _aIssued also as CD
653 4 _aCommon warts
653 4 _aIntralesional MMR vaccine
653 4 _aOral zinc
700 0 _aAhmed Mohammed Nada ,
_eSupervisor
700 0 _aMarwa Safwat Elhawary ,
_eSupervisor
700 0 _aSarah Ibrahim Ismail ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c73639
_d73639