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_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aM.Sc | ||
099 | _aCai01.11.04.M.Sc.2019.La.E | ||
100 | 0 | _aLaila Sulaiman Saleh Bashuqair | |
245 | 1 | 0 |
_aElevated NT-pro BNP plasma level as a marker of acute and sub-acute ventricular affection in breast cancer patients receiving chemotherapy / _c Laila Sulaiman Saleh Bashuqair ; Supervised Magdy Abdelhamid , Ghada Sayed Mahmoud , Dina Hesham Ahmed Soliman |
246 | 1 | 5 | _aفي البلازما كمؤشر لتأثر البطين الحاد و تحت الحاد في مريضات سرطان الثدي اللاتي يأخدنا علاجا كيميائيا ( NT-pro BNP )ارتفاع هرمون |
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_aCairo : _bLaila Sulaiman Saleh Bashuqair , _c2019 |
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_a107 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology | ||
520 | _aBackground: Chemotherapeutic agents used for treatment of breast cancer have many side effects, among them is cardiomyopathy. Despite that ejection fraction (EF) is a widely accepted echocardiographic method, yet it fails to detect subtle alterations of LV function. There comes a need for a more sensitive tool for detection of preclinical chemotherapy-induced cardiomyopathy. Purpose: Detection of preclinical LV systolic and/or diastolic dysfunction, using NT-BNP plasma level in breast cancer patients within 6 weeks after the initiation of their chemotherapeutic treatment. Methods: Seventy-four non-metastasizing breast cancer female patients with no cardiovascular risk factors were included. They were assessed right before taking their first chemotherapeutic session and 6 weeks thereafter. Assessment included age, two-dimensional (2D) as well as three-dimensional (3D) echocardiography. Blood samples for NT-BNP plasma level were collected before and 6 weeks after the initiation of chemotherapy. Samples were later analyzed using a Sandwich ELISA technique | ||
530 | _aIssued also as CD | ||
653 | 4 | _aBreast cancer | |
653 | 4 | _aLV dysfunction | |
653 | 4 | _aNT-BNP plasma level | |
700 | 0 |
_aDina Hesham Ahmed Soliman , _eSupervisor |
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700 | 0 |
_aGhada Sayed Mahmoud , _eSupervisor |
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700 | 0 |
_aMagdy Abdelhamid , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
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_aAsmaa _eCataloger |
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_aNazla _eRevisor |
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_2ddc _cTH |
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_c73797 _d73797 |