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| 003 | EG-GiCUC | ||
| 005 | 20250223032357.0 | ||
| 008 | 190914s2019 ua d f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.08.06.M.Sc.2019.No.S | ||
| 100 | 0 | _aNoha Mohamed Taha Mohamed Abbas | |
| 245 | 1 | 2 |
_aA Study on the potential synergistic combination of Ý-lactam antibiotics with metallic nanoparticles against multi-drug resistant bacteria / _cNoha Mohamed Taha Mohamed Abbas ; Supervised Mohammed Abdelhaleem Ramadan , Yasser Elmohammadi Ragab , Walaa Said Mohamed Abdelaal |
| 246 | 1 | 5 | _aدراسة مدى الفاعلية المحتملة لاتحاد البيتالاكتام مع الجزيئات النانومترية للمعادن ضد البكتريا المتعددة المقاومة للمضادات الحيوية |
| 260 |
_aCairo : _bNoha Mohamed Taha Mohamed Abbas , _c2019 |
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| 300 |
_a197 P. : _bcharts ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology | ||
| 520 | _aThe emergence of bacterial resistance against antibiotics happened due to the misuse of them, so the aim of the study was to discover a new strategy to solve the problem, such as a novel antimicrobial nano-composite with greater. For this purpose, a total of 48 isolates were collected from Elkasr Elainy hospital and identified as Staphylococcus aureus, Pseudomonas aeruginosa and Klebseilla pneumoniae, antibiotic susceptibility was carried out, ampicillin and cefalexin were selected for conjugation with silver nanoparticles as the majority of isolates showed resistance against them, and silver nano particles were prepared by the chemical reduction method. Then, silver nanoparticles were functionalized with ampicillin and cefalexin, Transmission Electron Microscopy, UV spectroscopy, zetasizer and Fourier transform infrared spectroscopy were used for characterization before and after conjugation with antibiotics, thier antibacterial activity alone, and after combination with antibiotics were determined. The data showed that antibiotic{u2013} silver nano conjugateincreased the bactericidal efficacy of antibiotics to 30 {u2013}to 100 fold higher than the antibiotics alone, In addition, invivo study showed efficient results of antibiotic-silver nano conjugated formula for wound healing, compared to dermazin cream | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aMulti-drug | |
| 653 | 4 | _aNanoparticles | |
| 653 | 4 | _aÝ-lactam | |
| 700 | 0 |
_aMohammed Abdelhaleem Ramadan , _eSupervisor |
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| 700 | 0 |
_aWalaa Said Mohamed Abdelaal , _eSupervisor |
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| 700 | 0 |
_aYasser Elmohammadi Ragab , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
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_aNazla _eRevisor |
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_aShimaa _eCataloger |
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_2ddc _cTH |
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_c73857 _d73857 |
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