| 000 | 02899cam a2200349 a 4500 | ||
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| 003 | EG-GiCUC | ||
| 005 | 20250223032402.0 | ||
| 008 | 190918s2019 ua dh f m 000 0 eng d | ||
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_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.28.Ph.D.2019.Ma.A | ||
| 100 | 0 | _aMarwa Mohamed Yahia Qwema | |
| 245 | 1 | 0 |
_aAssessment of myocardial functions and biological markers in newborns with hypoxic-ischemic encephalopathy / _cMarwa Mohamed Yahia Qwema ; Supervised Iman Ahmed Ehsan Abdelmeguid , Abdelrahmman Ahmed Abdelrazek , Olfat Gameil Shaker |
| 246 | 1 | 5 | _aتقييم وظائف عضلة القلب و الدلالات البيولوجية فى الاطفال حديثى الولادة المصابين بتلف فى الدماغ الناجم عن نقص الاكسجين الاقفارى و نقص تروية الدماغ |
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_aCairo : _bMarwa Mohamed Yahia Qwema , _c2019 |
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| 300 |
_a135 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
| 520 | _aIntroduction: Neonatal hypoxic ischemic encephalopathy is a major cause of chronic disability in childhood. Myocardial functions are affected by hypoxia. Signs of myocardial dysfunction depend on the severity of the injury. Objectives: the current study is designed to assess myocardial performance of full- term newborns with hypoxic- ischemic encephalopathy using echocardiography and cardiac troponin I and find out the relationship with HIE stages and also to analyze the association of the disease and its clinical stages with nitric oxide synthase(NOS) gene polymorphism. Material and methods: Thirty asphyxiated full-term newborns were consecutively enrolled in this study and another cross-matched twenty normal newborns as control group. All subjects were subjected to echocardiographic assessment of myocardial functions, measurement of serum cTnI and and DNA extraction from whole blood. Results: The systolic and diastolic functions were significantly impaired in the studied patients in comparison with controls(p<0.001). There was significant impairment in systolic functions in stage III HIE cases as regards FS%, EF%, TAPSE and MAPSE(p<0.001, p<0.001, p=0.007 and p=0.003 respectively). Also, there was significant impairment in diastolic function in stage III HIE cases as regard deceleration time(p=0.002) | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aEchocardiography | |
| 653 | 4 | _aHypoxic-ischemic encephalopathy | |
| 653 | 4 | _aMyocardial function | |
| 700 | 0 |
_aAbdelrahmman Ahmed Abdelrazek , _eSupervisor |
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| 700 | 0 |
_aIman Ahmed Ehsan Abdelmeguid , _eSupervisor |
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| 700 | 0 |
_aOlfat Gameil Shaker , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c73989 _d73989 |
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