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003			EG-GiCUC
005			20250223032423.0
008			191024s2019 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.19.05.M.Sc.2019.Me.A
100	0		_aMennatallah Mamdouh Shamma
245	1	0	_aAssessment of cognitive function in childhood acute lymphoblastic leukemia survivors National cancer institute, Egypt / _cMennatallah Mamdouh Shamma ; Supervised Mohamed Fawzy Ibrahim , Ahmed Mohamed Kamel , Doaa Riad Ayoub
246	1	5	_aتأثير العلاج الكيمائى على إدراك مرضى اللوكيميا الليمفاوية الحادة بالدم فى الأطفال المتعافين بالمعهد القومى للأورام - مصر
260			_aCairo : _bMennatallah Mamdouh Shamma , _c2019
300			_a137 P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520			_aIntroduction: Acute lymphoblastic leukemia (ALL) survivors experience cognitive deficits that can last for many years after the completion of chemotherapy. The etiology of this problem is largely unknown. However some risk factors were documented as age at diagnosis, gender and intensity of chemotherapy. Objective: This study aimed to assess cognitive functioning in childhood patients with ALL who have been treated with chemotherapy. Patients and methods: In the study 95 child aged between 6 and 12 years old, completed the Arabic version of Wechsler Intelligence Scale for children (WISC III), to assess cognitive functions and correlation between cognitive function scores and different variables; demographic, protocol given, duration of therapy{u2026}etc. Sixty-one children were ALL survivors at the pediatric oncology department at National cancer institute NCI, Cairo university compared to thirty-four were Control group consisted of healthy children from the same age group. Study patients have successfully accomplished their treatment protocol and were in complete remission during the evaluation for {u2265} 2 years under follow up without relapse and no pre-diagnosis history of neurodevelopmental disorder or psychiatric disorders which were excluded by children behavior Check List. Results: Study patients obtained WISC-III Total Intelligence Quotient (IQ) scores significantly below levels for their matched controls. The difference between patients and controls was significant (p < 0.001) for the following measures: Total IQ, Verbal IQ, Performance IQ scores, (84.8± 10 vs 98.7±10.3), (94.4±13.5 vs 110.1±13.6) and (76.6±10 vs 85.5±8.5) respectively. Among ALL survivors sex was considered a risk factor where females performed worse than males in verbal IQ with significant p value 0.045
530			_aIssued also as CD
653		4	_aAcute lymphoblastic leukemia
653		4	_aChildren
653		4	_aWechsler intelligence scale for children WISC III
700	0		_aAhmed Mohamed Kamel , _eSupervisor
700	0		_aDoaa Riad Ayoub , _eSupervisor
700	0		_aMohamed Fawzy Ibrahim , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c74728 _d74728