000 | 02793cam a2200349 a 4500 | ||
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003 | EG-GiCUC | ||
005 | 20250223032435.0 | ||
008 | 191112s2019 ua dh f m 000 0 eng d | ||
040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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041 | 0 | _aeng | |
049 | _aDeposite | ||
097 | _aPh.D | ||
099 | _aCai01.11.28.Ph.D.2019.Me.A | ||
100 | 0 | _aMehan Abdalla Mohamed | |
245 | 1 | 0 |
_aAssessment of cardiac functions and arrhythmia in clinically asymptomatic children with beta-thalassemia major and beta-thalassemia intermedia / _cMehan Abdalla Mohamed ; Supervised Khaled Mohamed Salama , Rasha Abdelraouf Abdelaziz , Hadeel Mohamed Seif Eldin |
246 | 1 | 5 | _aتقييم وظائف القلب وعدم انتظام ضربات القلب فى الاطفال مرضى انيميا البحر المتوسط الكبرى والوسطى |
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_aCairo : _bMehan Abdalla Mohamed , _c2019 |
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_a125 P. : _bcharts , facsimiles ; _c25cm |
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502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
520 | _aBack ground: Heart disease remains the major cause of morbidity and mortality in thalassemic patients. Heart injuries in iron overload cases include dilatation of the atria and ventricles, arrhythmia, pulmonary hypertension, systolic/diastolic dysfunction and finally heart failure. Echocardiographic techniques are non invasive, widely available and can be used to assess cardiac function. Assessment of cardiac iron load can be performed directly using Cardiac Magnetic resonance imaging T2* (CMRIT2*), a sensitive, noninvasive imaging, to correlate the cardiac iron status to echocardiographic and holter {uFB01}ndings. Aim: Assessment of cardiac functions and arrhythmia in children with Ý-Thalassemia Major and Ý-Thalassemia Intermedia and its correlation to CMRIT2* data as an indicator for cardiac iron overload. Methods: In this cross-sectional study, 30 patients with Ý- thalassemia major (TM) and 30 patients with Ý-thalassemia intermedia (TI) underwent full history taking, clinical examination and laboratory tests including (complete blood count, ALT, AST, Bl. urea, s. creatinine and serum ferritin). All patients were evaluated using 24-hour ambulatory electrocardiogram monitoring (Holter) and echocardiography, while only 15 patients with Ý- TM and 15 patients with Ý- TI were evaluated using CMRIT2* | ||
530 | _aIssued also as CD | ||
653 | 4 | _aArrhythmia | |
653 | 4 | _aEchocardiography | |
653 | 4 | _aThalassemia | |
700 | 0 |
_aHadeel Mohamed Seif Eldin , _eSupervisor |
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700 | 0 |
_aKhaled Mohamed Salama , _eSupervisor |
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700 | 0 |
_aRasha Abdelraouf Abdelaziz , _eSupervisor |
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856 | _uhttp://172.23.153.220/th.pdf | ||
905 |
_aAsmaa _eCataloger |
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905 |
_aNazla _eRevisor |
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942 |
_2ddc _cTH |
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_c75138 _d75138 |