000			03386cam a2200349 a 4500
003			EG-GiCUC
005			20250223032442.0
008			191119s2019 ua d f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.19.05.M.Sc.2019.He.P
100	0		_aHeba Mahmoud Mahmoud
245	1	0	_aPulmonary metastatectomy in pediatric cancer patients at National Cancer Institute, Egypt. survival, outcome and prognostic factors / _cHeba Mahmoud Mahmoud ; Supervised Emad Nabil Ebeid , Abdelrahman Mohamed Abdelrahman , Asmaa Mohamed Hamoda
246	1	5	_aعوامل نذير ونتائج استئصال ثانوية الرئة فى مرضى الأورام بقسم الأطفال بالمعهد القومى للأورام بمصر
260			_aCairo : _bHeba Mahmoud Mahmoud , _c2019
300			_a118 , (25) P. : _bcharts ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520			_aIntroduction: Metastatic tumors account for approximately 80% of all lung tumors in children. Although a wide variety of sarcomas and embryonal tumors of childhood produce lung metastases in children, Wilm{u2019}s tumor and osteosarcoma are the most frequent. While some metastatic lung nodules are excised for diagnosis and staging, others are removed as a part of oncologic management to achieve long-term survival and effect cure. Aim of Work: Assessment of prognostic factors of pulmonary metastatectomy in pediatric solid tumors as age, number, size, site, laterality, resectability of pulmonary nodules and number of Thoracotomies. Calculate overall survival (OS) among Patients who underwent pulmonary metastatectomy. Correlation of different prognostic factors with overall survival. Patients and Methods: Retrospective study included all patients with metastatic solid tumors to lungs who were treated at pediatric oncology and surgical departments, national Cancer Institute, Cairo University from 2008 to 2014 with resectable lung disease based on C.T chest and lung is the only site of metastasis. Results: Fifty five patients were included,43 were Osteosarcoma (78.2{u2105}), 5 cases Synovial sarcoma(9.1{u2105}),2 cases Rhabdomyosarcoma (3.6{u2105}),2 cases Ewing Sarcoma(3.6{u2105}),2 cases Germ cell tumor (3.6{u2105})and 1 case was Wilm{u2019}s tumor(1.8{u2105}).There were 30 males (54.5{u2105})and 25 female 45.5%.The mean age was 15 years ranging from (4.5- 23) years. The site of primary disease was at lower limbs in 43 patients (78.2%), upper limbs in 5 patients and other sites as anterior chest wall, axillary area, paraspinal area and kidney. All of them underwent complete surgical resection of the primary disease with negative margin, 22 patients did amputation (all of them were osteosarcoma except one case was synovial sarcoma) with tumor necrosis less than 90% in 40 cases
530			_aIssued also as CD
653		4	_aLung tumors
653		4	_aOverall survival (OS)
653		4	_aPediatric Cancer Patients
700	0		_aAbdelrahman Mohamed Abdelrahman , _eSupervisor
700	0		_aAsmaa Mohamed Hamoda , _eSupervisor
700	0		_aEmad Nabil Ebeid , _eSupervisor
856			_uhttp://172.23.153.220/th.pdf
905			_aNazla _eRevisor
905			_aShimaa _eCataloger
942			_2ddc _cTH
999			_c75303 _d75303