000 02994cam a2200349 a 4500
003 EG-GiCUC
005 20250223032442.0
008 191120s2019 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2019.Ka.R
100 0 _aKatreen Rabea Mahrous
245 1 0 _aRed cell distribution width, platelet count and mean platelet volume as markers of neonatal sepsis /
_cKatreen Rabea Mahrous ; Supervised Emad Emil Ghobrial , Salma Elhouchi , Asmaa Ahmed Abdelaal
246 1 5 _aمعامل اختلاف حجم الخلايا الحمراء وعدد الصفائح الدموية وحجم الصفائح الدموية كعلامات للتسمم الدموى بالاطفال حديثى الولادة
260 _aCairo :
_bKatreen Rabea Mahrous ,
_c2019
300 _a125 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aBackground: Neonates are easily prone for bacterial infection. It remains one of the leading causes of morbidity and mortality both among term and preterm infants. Early diagnosis and treatment of the newborn infant with suspected sepsis are essential to prevent severe and life-threatening complications. Compared with the clear and valuable therapeutic options, the diagnosis of suspected neonatal sepsis is challenging. The aim of this study was to evaluate the diagnostic efficiency of platelet count, mean platelet volume (MPV) and red cell distribution width (RDW) for the prediction of neonatal sepsis. Methods: This cross-sectional study was done on 160 newborns divided into 3 groups: group A (57 newborns): proven neonatal sepsis, group B (51 newborns): probable neonatal sepsis and Group C (52 newborns): controls. All patients in the study were subjected to adequate assessment of history, full clinical examination, complete blood count including (MPV and RDW), C - reactive protein (CRP) and blood culture & CSF culture. Results: The baseline platelet count of septic cases was lower than controls with a statistically significant difference. The mean platelet count in the three groups was 171.53 ± 156.55, 180.25 ± 150.96 and 293.46 ± 157.49 (103/cmm), respectively (P< 0.001). The mean MPV values among the groups A, B and C were 11.21± 1.07, 10.92 ± 1.08 and 10.90 ± 1.12 fl, respectively (P= 0.174). The baseline MPV of septic cases was higher than controls with no statistically significant difference
530 _aIssued also as CD
653 4 _aMean platelet volume (MPV)
653 4 _aNeonatal sepsis
653 4 _aRed cell distribution width
700 0 _aAsmaa Ahmed Abdelaal ,
_eSupervisor
700 0 _aEmad Emil Ghobrial ,
_eSupervisor
700 0 _aSalma Elhouchi ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75324
_d75324