000 02858cam a2200325 a 4500
003 EG-GiCUC
008 191125s2019 ua d f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.11.28.M.Sc.2019.Ma.L
100 0 _aMarwa Shaaban Abdo Ali
245 1 0 _aLeukocyte esterase reagent strips for diagnosis of spontaneous bacterial peritonitis in pediatric patients with chronic liver disease /
_cMarwa Shaaban Abdo Ali ; Supervised Engy Adel Mogahed , Caroline Morkos Ghobrial , Noha Salah
246 1 5 _aاستخدام شرائط كاشف الكرات البيضاء فى تشخيص عدوى الغشاء البريتونى لدى الأطفال الذين يعانون من استسقاء بسبب أمراض الكبد المزمنة
260 _aCairo :
_bMarwa Shaaban Abdo Ali ,
_c2019
300 _a83 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
520 _aIntroduction: Spontaneous bacterial peritonitis (SBP) is a common problem in patients with chronic liver disease (CLD). Aim of work: To assess the accuracy of leukocyte esterase reagent strips (LERS) as a bedside test for rapid diagnosis of SBP in pediatric liver patients with ascites. Patients and methods: This was a cross-sectional study conducted on 39 children of both sexes with CLD and ascites with a total of 47 paracentesis procedures performed. All patients were subjected for proper history taking and clinical examination for symptoms and signs of ascitic fluid infection (AFI). Ascitic fluid examination was performed including cells, culture and LERS. Results: The age of our patients ranged between 2 months to 16 years. Thirty-four paracentesis procedures were diagnostic (72.3%), 8 were therapeutic (17%). Biliary atresia constituted the main cause of CLD (55.3%). The most common symptoms of AFI were fever, abdominal pain and dyspnea. Seven patients had SBP with PMNL>250 and LERS were positive in 13 patients. Positive LERS, ascitic fluid culture, high TLC and absolute staff count, were significant predictors of AFI. The diagnostic accuracy of LERS for AFI compared to PMNL >250 was 95%, sensitivity 100% and specificity 92.3%. Conclusion: LERS is a rapid, accurate and sensitive method for diagnosis of SBP. It is recommended as a bedside test for diagnosis of SBP to allow early and proper management
530 _aIssued also as CD
653 4 _aAscitic fluid infection
653 4 _aChildren
653 4 _aLeukocyte esterase reagent strips
700 0 _aCaroline Morkos Ghobrial ,
_eSupervisor
700 0 _aEngy Adel Mogahed ,
_eSupervisor
700 0 _aNoha Salah ,
_eSupervisor
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75463
_d75463