000			02837cam a2200325 a 4500
003			EG-GiCUC
008			191202s2019 ua do f m 000 0 eng d
040			_aEG-GiCUC _beng _cEG-GiCUC
041	0		_aeng
049			_aDeposite
097			_aM.Sc
099			_aCai01.12.04.M.Sc.2019.Ta.E
100	0		_aTaher Hosny Abdelhamid Ali
245	1	0	_aEvaluation and optimization of CT-based attenuation correction in myocardial perfusion tomographic imaging / _cTaher Hosny Abdelhamid Ali ; Supervised Wael M. Elshemey , Magdy M. Khalil , Abdo A. Elfiky
246	1	5	_aتقييم و تحسين التصوير المقطعى لتصوير تروية عضلة القلب المعتمد على تصحيح التوهين بالتصوير المقطعى المحسوب
260			_aCairo : _bTaher Hosny Abdelhamid Ali , _c2019
300			_a88 P. : _bcharts , photographs ; _c25cm
502			_aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics
520			_aSPECT myocardial perfusion imaging (SPECT MPI) is a widely used and well-established method for the evaluation of patients with known or suspected coronary artery disease (CAD). The integration of SPECT and CT (low-dose multi-slice CT) can improve the quality of MPI by enabling attenuation correction from CT-mapping of the thorax. Collimator depth dependent, tissue attenuation, and scattered photons are the main image degrading factors in nuclear medicine procedures. Recently, iterative reconstruction algorithms include corrections in the clinical procedures, thus improving imaging quality and diagnostic accuracy. To evaluate the impact of iterative reconstruction corrected for attenuation, scatter and collimator depth dependent, cardiac phantom of 110 ml volume and wall thickness of 10mm was used. Further, two solid defects (transmural 45{u00B0}x 1.5 cm and non-transmural 60{u00B0}x 2 cm and 5 mm wall thickness) was inserted and the whole phantom located inside available cylindrical phantom. Clinically relevant activity was injected into myocardium walls and background. Clinical standard protocol was performed with SPECT imaging scan. Different acquisition parameters (e.g. time/projection and number of projections) were applied. Reconstruction was done applying conventional method and iterative reconstruction with different combination of corrections. Figures of merit were used to evaluate MPI image quality
530			_aIssued also as CD
653		4	_aCoronary artery disease (CAD)
653		4	_aCT-based attenuation correction
653		4	_aSPECT myocardial perfusion imaging (SPECT MPI)
700	0		_aAbdo A. Elfiky , _eSupervisor
700	0		_aMagdy M. Khalil , _eSupervisor
700	0		_aWael M. Elshemey , _eSupervisor
905			_aNazla _eRevisor
905			_aSamia _eCataloger
942			_2ddc _cTH
999			_c75601 _d75601