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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.05.M.Sc.2019.En.O
100 0 _aEnas Nagi Gaafar
245 1 0 _aOutcome of pediatric patients with rhabdomyosarcoma at National Cancer Institute, Egypt /
_cEnas Nagi Gaafar ; Supervised Hossam Eldeen Ahmed Abdelmonem , Amr Abdalla Salem , Ebraheem Abdalrahman Ebraheem
246 1 5 _aنتائج علاج الأطفال المرضى بالساركوما العضلية بالمعهد القومى الأورام. مصر
260 _aCairo :
_bEnas Nagi Gaafar ,
_c2019
300 _a105 P. :
_bcharts , facimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology
520 _aBackground: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in infants and children. It is the third most common solid tumor in children after neuroblastoma and Wilms tumor, making up 10-15% of all solid pediatric tumors. RMS incidence follows a bimodal age pattern. The first window of increased incidence, which accounts for more than 50% of cases, occurs in the first decade. This period peaks at a median of 2 years of age and consists mainly of embryonal (E-RMS) or botryoid RMS (B-RMS). The second peak occurs during adolescence and more commonly consists of alveolar RMS (A-RMS).Objectives: - To assess OS, EFS and DFS with a minimum one year follow up from the last patient.To identify the relationships between different demographic variables with OS, EFS and DFS to identify relevant prognostic factors. To detect relationships between survival rates and different modalities of local control (surgery, radiation therapy or both). Patients and methods: This is a retrospective study to evaluate treatment outcome of patients below 18 years of age, newly diagnosed with rhabdomyosarcoma who were treated at pediatric oncology department, National Cancer Institute (NCI), Cairo University, Egypt during the period from January 2012 to December 2016 Results: 54 pediatric patients with RMS with age ranging from 7 months to 17 years (median age 5 years) were studied. The median follow up period ranged with a median of one year for the last patient
530 _aIssued also as CD
653 4 _aCombined modality therapy
653 4 _aIRS risk grouping
653 4 _aRhabdomyosarcoma in pediatric patients
700 0 _aAmr Abdalla Salem ,
_eSupervisor
700 0 _aEbraheem Abdalrahman Ebraheem ,
_eSupervisor
700 0 _aHossam Eldeen Ahmed Abdelmonem ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75696
_d75696