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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aM.Sc
099 _aCai01.19.04.M.Sc.2019.No.C
100 0 _aNoha Saeed Ali Mohamed
245 1 0 _aClinical utility of interferon gamma assay for early detection of tuberculosis in immunocompromised cancer patients /
_cNoha Saeed Ali Mohamed ; Supervised Magdy Mohammed Saber , Hadir Almahalawy , Hala Aziz Shokralla
246 1 5 _aالفائذة الاكلينيكيه استخذام الاوتيرفيرون جاما للاكتشاف المبكر لمرض الدرن فى مرضى السرطان المصاحب لىقص المناعة
260 _aCairo :
_bNoha Saeed Ali Mohamed ,
_c2019
300 _a97 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical)
520 _aIntroduction Tuberculosis (TB) is an infectious disease that usually affects the lungs, the relationship between TB and cancer is of dual nature. Patients with malignant diseases have an increased risk for diseases caused by TB. Patients with depressed cellular immunity such as those who have lymphoproliferative disorders, transplant patients and patients on immunosuppressive therapy are at particular risk. For latent tuberculosis infection (LTBI) diagnosis, interferon gamma release assay (IGRAs) may be used as part of the overall risk assessment to identify individuals for preventive treatment (Hong et al, 2016). Patients and methods Quantiferon test was done for two immunosuppression group: solid malignancy (30 patients) and hematological malignancy (30 patient), followed with PCR sputum for positive patient to differentiate active from latent tuberculosis. Results Twenty patients were positive (11 solid cancers and 9 hematological malignancy) with p value 0.540, only two patients from them positive PCR
530 _aIssued also as CD
653 4 _aHematological malignancy
653 4 _aLatent tuberculosis
653 4 _aSolid cancers
700 0 _aHadir Almahalawy ,
_eSupervisor
700 0 _aHala Aziz Shokralla ,
_eSupervisor
700 0 _aMagdy Mohammed Saber,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c75807
_d75807