| 000 | 02473cam a2200349 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032520.0 | ||
| 008 | 200206s2019 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
||
| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aPh.D | ||
| 099 | _aCai01.11.28.Ph.D.2019.Az.S | ||
| 100 | 0 | _aAzza Omar Abdelaziz Tora | |
| 245 | 1 | 0 |
_aSerum level of fibroblast growth factor receptor-4 as a predictor for bronchopulmonary dysplasia and its correlation with its polymorphism / _cAzza Omar Abdelaziz Tora ; Supervised Iman Eyada , May khairy , Walaa Aboulkasem Shahin |
| 246 | 1 | 5 | _aقياس نسبه المستقبل 4 لعامل نمو الخلايا الليفيه فى الدم كمتنبأ لحدوث الخلل الشعبى الرئوى وعلاقته بخصائصه الجينيه |
| 260 |
_aCairo : _bAzza Omar Abdelaziz Tora , _c2019 |
||
| 300 |
_a143 P. : _bcharts , facsimiles ; _c25cm |
||
| 502 | _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics | ||
| 520 | _aBPD is the result of a complex process in which severalprenatal and/or postnatal factors interfere with lower respiratorytract development, leading to a severe, lifelong disease.(Principi et al., 2018) The underlying etiology is multifactorial; it is influenced by both genetic susceptibility and environmental factors on the immature lung. The pathophysiology is characterized by inflammation, abnormal microvascularization, and impaired alveolarization. (Rezvaniet al., 2013) Fibroblast growth factors (FGFs) are secreted glycoproteinsinvolved in interactions between epithelium and mesenchymeregulating cell migration and proliferation in embryonicdevelopment, especially in fetal pulmogenesis.Their signalling depends on membrane-located receptors(FGFRs) with a tyrosine kinase domain, encoded by fourdifferent genes (FGFR 1{u2013}4).They are all translatedin developing lungs and are suggested to play major rolesin modifying distal lung patterns during alveolarization | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aBronchopulmonary dysplasia (BPD) | |
| 653 | 4 | _aFGFR | |
| 653 | 4 | _aFibroblast growth factor receptor-4 as a predictor | |
| 700 | 0 |
_aIman Eyada , _eSupervisor |
|
| 700 | 0 |
_aMay khairy , _eSupervisor |
|
| 700 | 0 |
_aWalaa Aboulkasem shahin , _eSupervisor |
|
| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
||
| 905 |
_aShimaa _eCataloger |
||
| 942 |
_2ddc _cTH |
||
| 999 |
_c76540 _d76540 |
||