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040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.19.03.Ph.D.2019.Mo.C
100 0 _aMohamed Abdelmohsen Zaki Mostafa
245 1 0 _aCD163 versus CD68 immunohistochemistry in predicting outcome in classical hodgkin lymphoma in Egyptian patients /
_cMohamed Abdelmohsen Zaki Mostafa ; Supervised Nahed Abdelwahab , Osman Mansour , Reham Ahmed Rashed
246 1 5 _aالدراسة الكيمائية المناعية للانسجة ل 163 سي دى مقابل68 سي دى فى التنبؤ بتطور المرض فى سرطان هودجكين الكلاسيكى بالغدد الليمفاوية فى المرضى المصريين
260 _aCairo :
_bMohamed Abdelmohsen Zaki Mostafa ,
_c2019
300 _a233 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology
520 _aBackground: Hodgkin's Lymphoma is a malignant tumor of the lymphatic system, first recorded by Thomas Hodgkin in 1832. Tumor associated macrophages have been implicated in the pathogenesis of Classical Hodgkin Lymphoma and have been suggested to have a negative impact on outcome. CD 163 and CD 68 markers of the monocyte/macrophage lineage have been used to evaluate tumor associated macrophages. Aim of the study: The aim of this study is to determine the expression and the prognostic impact of CD 163 and CD 68 in the initial bone marrow biopsy specimens of our subjects by immunohistochemistry and to correlate their expression with other clinical and laboratory prognostic factors. Subjects and Methods: This study was conducted on fifty one patients with de novo Classical Hodgkin Lymphoma, presenting to the Clinical Pathology Department at the National Cancer Institute, Cairo university. CD 163 and CD 68 were detected in the initial bone marrow biopsy specimens from our subjects by immunohistochemistry
530 _aIssued also as CD
653 4 _aCD163
653 4 _aCD68
653 4 _aHodgkin Lymphoma
700 0 _aNahed Abdelwahab ,
_eSupervisor
700 0 _aOsman Mansour ,
_eSupervisor
700 0 _aReham Ahmed Rashed ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aAsmaa
_eCataloger
905 _aNazla
_eRevisor
942 _2ddc
_cTH
999 _c76857
_d76857