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008 200508s2019 ua dh f m 000 0 eng d
040 _aEG-GiCUC
_beng
_cEG-GiCUC
041 0 _aeng
049 _aDeposite
097 _aPh.D
099 _aCai01.11.15.Ph.D.2019.Ba.C
100 0 _aBassem Mohamed Hassanain
245 1 0 _aCorrelation between ultrasonographic fetal soft markers and aneuploidy /
_cBassem Mohamed Hassanain ; Supervised Maha Mohamed Mosaad Farag , Yasmin Ahmed Bassiouny , Ayman Mohamed Taher
246 1 5 _aالإرتباط بين العلامات الغير مؤكدة بالجنين فى الموجات فوق الصوتية وإختلال الصيغه الصبغيه
260 _aCairo :
_bBassem Mohamed Hassanain ,
_c2019
300 _a124 P. :
_bcharts , facsimiles ;
_c25cm
502 _aThesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics
520 _aUltrasound screening in the second trimester to identify fetal anomalies has developed and improved remarkably over the last few decades; moreover, it is possible to detect even minor structural abnormalities. Some sonographic findings are structural signs with little or no pathological significance. Such signs, commonly known as 2soft markers,3 are more often found in fetuses with congenital anomalies and are associated with chromosomal abnormalities.This is an Observational prospective cross sectional study preformed on 100 pregnant women from 16-24 weeks of gestation with one sonographic fetal soft marker or moredetected in their mid trimester anomaly scan and followed up till delivery to evaluate the usefulness of each ultrasound soft marker, assess whether a specific soft marker should be looked for routinely on screening ultrasound.Three cases of the studied group were associated with structural fetal anomalies (2 cases of them were associated with echogenic intracardiac foci , pyelectasis and Congenital heart disease and one case was associated with echogenic intracardiac focus , short long bones and omphalocele ), two cases of them were discovered post- natally to be Down syndrome.It is concluded from the study that many soft markers will disappear or regress as gestation proceeds.The persistence or disappearance of a marker does not alter the risk of aneuploidy when it is isolated. But if combined soft markers are detected especially if associated with structural congenital anomaly, karyotyping should be offered for the newborn
530 _aIssued also as CD
653 4 _aAneuploidy
653 4 _aSoft markers
653 4 _aUltrasonographic fetal soft markers
700 0 _aAyman Mohamed Taher ,
_eSupervisor
700 0 _aMaha Mohamed Mosaad Farag ,
_eSupervisor
700 0 _aYasmin Ahmed Bassiouny ,
_eSupervisor
856 _uhttp://172.23.153.220/th.pdf
905 _aNazla
_eRevisor
905 _aShimaa
_eCataloger
942 _2ddc
_cTH
999 _c77087
_d77087