| 000 | 02579cam a2200337 a 4500 | ||
|---|---|---|---|
| 003 | EG-GiCUC | ||
| 005 | 20250223032549.0 | ||
| 008 | 200829s2020 ua dh f m 000 0 eng d | ||
| 040 |
_aEG-GiCUC _beng _cEG-GiCUC |
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| 041 | 0 | _aeng | |
| 049 | _aDeposite | ||
| 097 | _aM.Sc | ||
| 099 | _aCai01.12.10.M.Sc.2020.Ya.F | ||
| 100 | 0 | _aYassmen Abdelsalam Elsayed Mohamed | |
| 245 | 1 | 0 |
_aFormation of sensitive nanoparticles based on Alginate derivatives to be used as drug delivery systems / _cYassmen Abdelsalam Elsayed Mohamed ; Supervised Riham Rashad Mohamed Ali , Soliman Mehawed Abdellatif Soliman |
| 246 | 1 | 5 | _aتكوين جسيمات نانوية حساسة مبنية على مشتقات اللألجيىات لأستخدامها كأنظمه موصله للعقاقير |
| 260 |
_aCairo : _bYassmen Abdelsalam Elsayed Mohamed , _c2020 |
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| 300 |
_a80 P. : _bcharts , facsimiles ; _c25cm |
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| 502 | _aThesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry | ||
| 520 | _aSodium alginate was modified using grafting technique and by chemical modification. Firstly, Acrylonitrile was grafted onto sodium alginate to obtain amphiphilic copolymer SA-g-PAN. The kinetic parameters of grafting process included monomer concentration, initiator concentration, reaction temperature and time were studied. The grafting parameters such as the percent graft yield (% G), percent graft efficiency (% GE) and percent homopolymer (% H) were calculated and determined the optimum conditions for grafting process. The copolymer was characterized using FTIR spectroscopy, XRD and thermogravimetric analysis. Nanoparticles based on prepared SA-g-PAN were formed through nanoprecipitation technique and characterized by Transmission electron microscope (TEM) and then hydrophobic model was encapsulated Secondly, modification of sodium alginate has been done through cations-exchange between sodium ions and p-phenylenediamine hydrochloride salt. The modified alginate (PPD-SA) was characterized using FTIR spectroscopy, XRD and thermogravimetric analysis. Nanoparticles based on the modified alginate was formed via nanoprecipitation technique and cytotoxicity was tested | ||
| 530 | _aIssued also as CD | ||
| 653 | 4 | _aAcrylonitrile | |
| 653 | 4 | _aGrafting | |
| 653 | 4 | _aSodium alginate | |
| 700 | 0 |
_aRiham Rashad Mohamed Ali , _eSupervisor |
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| 700 | 0 |
_aSoliman Mehawed Abdellatif Soliman , _eSupervisor |
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| 856 | _uhttp://172.23.153.220/th.pdf | ||
| 905 |
_aNazla _eRevisor |
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| 905 |
_aShimaa _eCataloger |
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| 942 |
_2ddc _cTH |
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| 999 |
_c77446 _d77446 |
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